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DOI: http://dx.doi.org/10.4081/dr.2011.e41

Hyperimmunoglobulin E syndrome in two siblings

Abdulmohti Hawilo, Ines Zaraa, Sondes Trojjet, Hella Zribi, Rym Cheikh Rouhou, Dalenda El Euch, Mourad Mokni, Amel Ben Osman


Hyperimmunoglobulin E recurrent infection syndrome (HIES) is characterized by recurrent skin and lung infections, eczema, elevated serum immunoglobulin E (IgE) levels (>2000 IU/mL), various connective tissue, skeletal, and vascular abnormalities.1 We describe herein two brothers with HIES and documented the complications and management of such involvement.


hyper-IgE syndrome, atopic dermatitis, primary immunodeficiency, infection.

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Submitted: 2011-07-20 00:32:19
Published: 2011-11-28 14:00:56
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Dermatology Reports [eISSN 2036-7406] is an Open Access, peer-reviewed journal published by PAGEPress, Pavia, Italy. All credits and honors to PKP for their OJS.



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