Hyperimmunoglobulin E syndrome in two siblings


https://doi.org/10.4081/dr.2011.e41
Vol. 3 No. 3 (2011)
Submitted: 20 July 2011
Accepted: 12 September 2011
Published: 28 November 2011
hyper-IgE syndrome, atopic dermatitis, primary immunodeficiency, infection.
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Authors

  • Abdulmohti Hawilo Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia.
  • Ines Zaraa
    inesrania@myway.com
    Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia.
  • Sondes Trojjet Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia.
  • Hella Zribi Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia.
  • Rym Cheikh Rouhou Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia.
  • Dalenda El Euch Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia.
  • Mourad Mokni Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia.
  • Amel Ben Osman Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia.
Hyperimmunoglobulin E recurrent infection syndrome (HIES) is characterized by recurrent skin and lung infections, eczema, elevated serum immunoglobulin E (IgE) levels (>2000 IU/mL), various connective tissue, skeletal, and vascular abnormalities.1 We describe herein two brothers with HIES and documented the complications and management of such involvement.

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Hawilo, A., Zaraa, I., Trojjet, S., Zribi, H., Rouhou, R. C., El Euch, D., Mokni, M., & Ben Osman, A. (2011). Hyperimmunoglobulin E syndrome in two siblings. Dermatology Reports, 3(3), e41. https://doi.org/10.4081/dr.2011.e41

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