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Hyperimmunoglobulin E syndrome in two siblings

Abdulmohti Hawilo, Ines Zaraa, Sondes Trojjet, Hella Zribi, Rym Cheikh Rouhou, Dalenda El Euch, Mourad Mokni, Amel Ben Osman
  • Abdulmohti Hawilo
    Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia
  • Ines Zaraa
    Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia | inesrania@myway.com
  • Sondes Trojjet
    Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia
  • Hella Zribi
    Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia
  • Rym Cheikh Rouhou
    Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia
  • Dalenda El Euch
    Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia
  • Mourad Mokni
    Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia
  • Amel Ben Osman
    Dermatology Department, La Rabta, Hospital,Faculté de Médecine, Université El Manar, Tunis, Tunisia

Abstract

Hyperimmunoglobulin E recurrent infection syndrome (HIES) is characterized by recurrent skin and lung infections, eczema, elevated serum immunoglobulin E (IgE) levels (>2000 IU/mL), various connective tissue, skeletal, and vascular abnormalities.1 We describe herein two brothers with HIES and documented the complications and management of such involvement.

Keywords

hyper-IgE syndrome, atopic dermatitis, primary immunodeficiency, infection.

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Submitted: 2011-07-20 00:32:19
Published: 2011-11-28 14:00:56
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Copyright (c) 2011 Abdulmohti Hawilo, Ines Zaraa, Sondes Trojjet, Hella Zribi, Rym Cheikh Rouhou, Dalenda El Euch, Mourad Mokni, Amel Ben Osman

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