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Complications of percutaneous endoscopic gastrostomy-jejunostomy for levodopa/carbidopa infusion in advanced Parkinson's disease
Ana Olivares, David Collado, Miguel Muñoz-Navas, Marta Calvo, Eduardo Olivo, Inmaculada Chico, Carlos Marra, Rafael Sánchez-Estella, Sarbelio Rodríguez, Josè Carlos Subtil, Luis Ramon Rábago
Authors information- Ana Olivares
Gastroenterology Department, Hospital Severo Ochoa, Leganés, Madrid, Spain. anaolivares84@hotmail.com
- David Collado
Gastroenterology Department, Hospital Severo Ochoa, Leganés, Madrid, Spain.
- Miguel Muñoz-Navas
Gastroenterology Department, Clínica Universidad de Navarra, Pamplona, Spain.
- Marta Calvo
Gastroenterology Department, Hospital Doce de Octubre, Madrid, Spain.
- Eduardo Olivo
Surgical Deparment, Hospital Severo Ochoa, Leganés, Madrid, Spain.
- Inmaculada Chico
Gastroenterology Department, Hospital Severo Ochoa, Leganés, Madrid, Spain.
- Carlos Marra
Gastroenterology Department, Clínica Universidad de Navarra, Pamplona, Spain.
- Rafael Sánchez-Estella
Surgical Deparment, Hospital Severo Ochoa, Leganés, Madrid, Spain.
- Sarbelio Rodríguez
Gastroenterology Department, Hospital Doce de Octubre, Madrid, Spain.
- Josè Carlos Subtil
Gastroenterology Department, Clínica Universidad de Navarra, Pamplona, Spain.
- Luis Ramon Rábago
Gastroenterology Department, Hospital Severo Ochoa, Leganés, Madrid, Spain.
Abstract
Continuous infusions of levodopa directly into the duodenum-yeyunum is an effective therapy to reduce daily off time in an advanced stage of Parkinson's disease, but it is not without complications, particularly device related problems. We present our experience in three Spanish hospitals with these complications, including a severe case with migration, several decubitus ulcers, and one case of perforation of the bowel and finally death.
Keywords
percutaneous endoscopic gastrostomy-tube, levodopa/carbidopa infusion in duodenum, intestinal obstruction, intestinal perforation, endoscopic extraction
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Submitted: 2011-08-16 20:04:14
Published: 2012-03-06 14:18:24
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Published: 2012-03-06 14:18:24
Search for citations in Google Scholar
Related articles: Google Scholar