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A rare case of three distinct Epstein-Barr virus associated lymphoproliferative disorders over sixteen years of human immunodeficiency virus infection

Hamdy M.A. Ahmed, Abrar Khan, Weyman Lam, Samar Abohamad, Pradyumna Phatak
  • Abrar Khan
    Department of Internal Medicine, Rochester General Hospital, Rochester, NY, United States
  • Weyman Lam
    Department of Internal Medicine, Rochester General Hospital, Rochester, NY, United States
  • Samar Abohamad
    Department of Internal Medicine, Cairo University Hospitals, Cairo, Egypt
  • Pradyumna Phatak
    Division of Hematology and Oncology, Department of Internal Medicine, Rochester General Hospital, Rochester, NY, United States

Abstract

Epstein Barr virus (EBV) is well known to cause different types of malignancies. In immunocompromised patients, such as those infected with human immunodeficiency virus (HIV), there is a higher likelihood of EBV related malignant transformation. Diagnosis of EBV related malignancies may be difficult and sometimes requires clinical and pathological correlation. It is very rare to have more than one type of EBV related malignancy in a single patient. Until now, there are no specific guidelines for treatment of EBV related malignancies and lymphoproliferative disorders (LPD). We present a patient who developed three different types of EBV related LPD during a sixteen-year course of HIV infection.

Keywords

EBV, HIV, lymphoproliferative disorders, lymphoma

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Submitted: 2016-11-27 02:59:36
Published: 2017-06-01 10:19:48
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Copyright (c) 2017 Hamdy Mohamed Abdelaziz Ahmed, Abrar Khan, Weyman Lam, Samar Abohamad, Pradyumna Phatak

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