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Invasive aspergillosis with disseminated skin ınvolvement in a patient with acute myeloid leukemia: a rare case

Duygu Mert, Gülşen Iskender, Fazilet Duygu, Alparslan Merdin, Mehmet Sinan Dal, Mehmet Doğan, Emre Tekgündüz, Mustafa Ertek, Fevzi Altuntaş
  • Duygu Mert
    Infectious Diseases and Clinical Microbiology, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey | drduygumert@hotmail.com
  • Gülşen Iskender
    Infectious Diseases and Clinical Microbiology, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey
  • Fazilet Duygu
    Infectious Diseases and Clinical Microbiology, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey
  • Alparslan Merdin
    Hematology Clinic and Bone Marrow Transplantation Unit, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey
  • Mehmet Sinan Dal
    Infectious Diseases and Clinical Microbiology, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey
  • Mehmet Doğan
    Department of Pathology, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey
  • Emre Tekgündüz
    Hematology Clinic and Bone Marrow Transplantation Unit, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey
  • Mustafa Ertek
    Infectious Diseases and Clinical Microbiology, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey
  • Fevzi Altuntaş
    Hematology Clinic and Bone Marrow Transplantation Unit, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey

Abstract

Invasive pulmonary aspergillosis is most commonly seen in immunocompromised patients. Besides, skin lesions may also develop due to invasive aspergillosis in those patients. A 49-year-old male patient was diagnosed with acute myeloid leukemia. The patient developed bullous and zosteriform lesions on the skin after the 21st day of hospitalization. The skin biopsy showed hyphae. Disseminated skin aspergillosis was diagnosed to the patient. Voricanazole treatment was initiated. The patient was discharged once the lesions started to disappear.

Keywords

Invasive aspergillosis; disseminated skin invasion; leukemia

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Submitted: 2016-12-13 20:39:58
Published: 2017-06-01 10:31:44
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Copyright (c) 2017 Duygu Mert, Gülşen Iskender, Fazilet Duygu, Alparslan Merdin, Mehmet Sinan Dal, Mehmet Dogan, Emre Tekgündüz, Mustafa Ertek, Fevzi Altuntaş

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