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Hairy cell lymphoma: a potentially under-recognized entity

William A. Hammond, Abhisek Swaika, David Menke, Han W. Tun
  • William A. Hammond
    Division of Hematology/Oncology, Mayo Clinic, Jacksonville, FL, United States
  • Abhisek Swaika
    Division of Hematology/Oncology, Mayo Clinic, Jacksonville, FL, United States
  • David Menke
    Division of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, FL, United States
  • Han W. Tun
    Division of Hematology/Oncology, Mayo Clinic, Jacksonville, FL, United States | tun.han@mayo.edu

Abstract

Hairy cell leukemia (HCL) is a low grade B-cell lymphoproliferative disorder that typically presents with splenomegaly, cytopenias, and diffuse bone marrow infiltration. There have been few cases in the literature of HCL presenting as lymphomas in extra-nodal locations, such as soft tissues and bones without circulating leukemic cells, splenomegaly, or iliac crest bone marrow involvement. We present an additional case presenting as a thoracic mass, and discuss potential diagnostic pitfalls and management of these rare cases.

Keywords

Lymphoma; B-cell lymphoproliferative disorder; splenomegaly; cytopenias; diffuse bone marrow infiltration

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Submitted: 2016-06-03 16:09:12
Published: 2017-03-28 16:17:20
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Copyright (c) 2017 William A. Hammond, Abhisek Swaika, David Menke, Han W. Tun

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