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Osteosclerosis secondary to metastatic oligodendroglioma

Patrick R. Maloney, Vitor Nagai Yamaki, Ravi Kumar, Derek Johnson, Christopher Hunt, Mark E. Jentoft, Michelle Clarke
  • Patrick R. Maloney
    Department of Neurosurgery, Mayo Clinic, College of Medicine, Rochester, MN, United States | maloney.patrick@mayo.edu
  • Vitor Nagai Yamaki
    Department of Neurosurgery, Mayo Clinic, College of Medicine, Rochester, MN, United States
  • Ravi Kumar
    Department of Neurosurgery, Mayo Clinic, College of Medicine, Rochester, MN, United States
  • Derek Johnson
    Department of Neurology, Mayo Clinic, College of Medicine, Rochester, MN, United States
  • Christopher Hunt
    Department of Neuroradiology, Mayo Clinic, College of Medicine, Rochester, MN, United States
  • Mark E. Jentoft
    Department of Anatomic Pathology, Mayo Clinic, College of Medicine, Rochester, MN, United States
  • Michelle Clarke
    Department of Neurosurgery, Mayo Clinic, College of Medicine, Rochester, MN, United States

Abstract

This paper reviews a case of metastatic 1p/19q codeleted oligodendrioglioma causing diffuse osteosclerosis and pain. Primary central nervous system (CNS) tumors rarely metastasize outside the CNS, and metastatic oligodendroglioma is rarer still. The patient in this study had relief of pain after being treated with temozolomide. We discuss this rare presentation and potential treatment options, and review the literature in regards to metastatic oligodendrogliomas.

Keywords

Oligodendroglioma; Osteosclerosis; 1p/19q; Metastasis

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Submitted: 2016-08-16 00:22:20
Published: 2017-03-31 09:01:16
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Copyright (c) 2017 Patrick R Maloney, Vitor Nagai Yamaki, Ravi Kumar, Derek R Johnson, Christopher H Hunt, Mark E Jentoft, Michelle J Clarke

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