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A case of pancreatic acinar cell carcinoma metastatic to skin

Minori Ikezoe, Tamao Nishihara, Kazunori Yanagawa, Takashi Kohro, Yuichi Yasunaga, Yoshiaki Inui, Masahiro Nishikawa
  • Minori Ikezoe
    Hyogo Prefectural Nishinomiya Hospital, Japan
  • Kazunori Yanagawa
    Hyogo Prefectural Nishinomiya Hospital, Japan
  • Takashi Kohro
    Hyogo Prefectural Nishinomiya Hospital, Japan
  • Yuichi Yasunaga
    Hyogo Prefectural Nishinomiya Hospital, Japan
  • Yoshiaki Inui
    Hyogo Prefectural Nishinomiya Hospital, Japan
  • Masahiro Nishikawa
    Hyogo Prefectural Nishinomiya Hospital, Japan

Abstract

We report a rare case of pancreatic acinar cell carcinoma with widespread metastases in a 68-year-old woman who presented with subcutaneous nodules as the initial symptom. Computed tomography showed a pancreatic mass with hepatic tumors and enlarged lymph nodes besides ring-enhanced subcutaneous nodules. Magnetic resonance diffusion-weighted imaging detected the presence of lesions in other organs. Histological analysis of a colonic polypoid lesion revealed carcinoma with endocrine and acinar differentiation compatible with pancreatic origin. Regrettably, she died of a cerebral infarction without any treatment, and autopsy findings confirmed our diagnosis.

Keywords

pancreatic acinar cell carcinoma; subcutaneous nodules;widespread metastases;

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Submitted: 2009-11-09 04:35:34
Published: 2010-11-08 09:08:05
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Copyright (c) 2010 Minori Ikezoe, Tamao Nishihara, Kazunori Yanagawa, Takashi Kohro, Yuichi Yasunaga, Yoshiaki Inui, Masahiro Nishikawa

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