Cutaneous larva migrans: is dermoscopy useful for the treatment?

Giulia Bazzacco; Carlotta Nardello; Raffaele Dante Caposiena Caro; Nicola Di Meo; Iris Zalaudek; Marina Agozzino

doi:10.4081/dr.2024.10049

Authors

Giulia Bazzacco
giuliabazzacco@gmail.com
Department of Dermatology, Ospedale Maggiore, University of Trieste, Italy. https://orcid.org/0000-0001-8135-7025
Carlotta Nardello Department of Dermatology, Ospedale Maggiore, University of Trieste, Italy. https://orcid.org/0000-0001-8380-0211
Raffaele Dante Caposiena Caro Department of Dermatology, Ospedale Maggiore, University of Trieste, Italy.
Nicola Di Meo Department of Dermatology, Ospedale Maggiore, University of Trieste, Italy.
Iris Zalaudek Department of Dermatology, Ospedale Maggiore, University of Trieste, Italy. https://orcid.org/0000-0002-7878-4955
Marina Agozzino Department of Dermatology, Ospedale Maggiore, University of Trieste, Italy. https://orcid.org/0000-0002-3753-1724

Cutaneous larva migrans (CLM) is a zoonotic disease endemic in tropical regions. CLM diagnosis mainly relies on the morphology of the skin lesions; however, dermoscopy can improve diagnostic accuracy. In this paper, we report two cases of CLM to highlight the importance of dermoscopic follow-up in the early identification of treatment failure and the effectiveness of topical ivermectin as a combined medication.

Leung AKC, Barankin B, Hon KLE. Cutaneous Larva Migrans. Recent Pat Inflamm Allergy Drug Discov 2017;11:2-11.

Conforti C, Dri A, Toffoli L, et al. Entodermoscopy: A Useful Tool for the Diagnosis of Cutaneous Larva Migrans. Dermatol Pract Concept 2021;11:e2021014.

Zalaudek I, Giacomel J, Cabo H, et al. Entodermoscopy: A new tool for diagnosing skin infections and infestations. Dermatology 2007;216:14-23.

Enechukwu NA, Ogun GO, Malachy DE, et al. Dermoscopic Characteristics of Cutaneous Larva Migrans in the Dark Skin: A Study from Banjul, The Gambia. Clin Exp Dermatol 2023:llad381.

Rather S, Aslam A, Younus F. Dermoscopy Before and After Treatment of Cutaneous Larva Migrans: Through the Dermoscope. Indian Dermatol Online J 2022;13:690-4.

Bouchaud O, Houzé S, Schiemann R, et al. Cutaneous larva migrans in travelers: a prospective study, with assessment of therapy with ivermectin. Clin Infect Dis 2000;31:493-8.

Sunderkötter C, von Stebut E, Schöfer H, et al. S1 guideline diagnosis and therapy of cutaneous larva migrans (creeping disease). J Dtsch Dermatol Ges 2014;12:86-91

Wesołowski R, Mila-Kierzenkowska C, Pawłowska M, et al. Cutaneous larva migrans imported from a tropical trip - Case report and literature review. Ann Agric Environ Med 2021;28:709-12.

Puente Puente S, Bru Gorraiz F, Azuara Solís M, et al. Larva migrans cutánea: 34 casos importados [Cutaneous larva migrans: 34 outside cases]. Rev Clin Esp 2004;204:636-9.

Gerbig AW, Kempf W. Topical treatment of cutaneous larva migrans with ivermectin 1. Int J Dermatol 2020;59:e21-e22.

Gelmetti C, Brena M, Veraldi S. Hookworm-related cutaneous larva migrans of the penis successfully treated with topical ivermectin. Pediatr Dermatol 2019;36:391-2.

Magri F, Chello C, Pranteda G, Pranteda G. Complete resolution of cutaneous larva migrans with topical ivermectin: A case report. Dermatol Ther 2019;32:e12845.

Smilga AS, Bujold J. A Unique Case of Cutaneous Larva Migrans Acquired Within the Province of Quebec and Successfully Treated With Topical Ivermectin. J Cutan Med Surg 2018;22:347-8.

Veraldi S, Angileri L, Parducci BA, Nazzaro G. Treatment of hookworm-related cutaneous larva migrans with topical ivermectin. J Dermatolog Treat 2017;28:263.

Bazzacco, G., Nardello, C., Caposiena Caro, R. D., Di Meo, N., Zalaudek, I., & Agozzino, M. (2024). Cutaneous larva migrans: is dermoscopy useful for the treatment?. Dermatology Reports, 17(1). https://doi.org/10.4081/dr.2024.10049