Acitretin systemic and retinoic acid 0.1% cream supression of basal cell carcinoma

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Xi-Bao Zhang *
San-Quan Zhang
Chang-Xing Li
Zhen-Ming Huang
Yu-Wu Luo
(*) Corresponding Author:
Xi-Bao Zhang | lilichangxing@163.com

Abstract

Retinoids have been used for years as monotherapy and/or in combination for treatment and suppression of cutaneous malignancies in patients with basal cell nevus syndrome, xeroderma pigmentosum, or cutaneous T-cell lymphoma (CTCL) basal cell carcinoma (BCC). We report 4 cases with BCC confirmed by histopathology who were treated by short-term systemic acitretin combined with retinoic acid 0.1% cream. The 4 cases with BCC showed good response to the treatment without severe adverse effects during treatment and follow-up. The finding suggests that acitretin may be an appropriate treatment option for elderly patients who require less invasive treatment for BCC.

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