Giant condyloma acuminate due human papilloma virus type 16 in an infant successfully treated with topical imiquimod therapy

  • Meltem Dinleyici | meltemayata@hotmail.com Department of Social Pediatrics, Eskisehir Osmangazi University, Turkey.
  • Nurhan Saracoglu Department of Dermatology, Eskisehir Osmangazi University, Turkey.
  • Makbule Eren Department of Pediatric Gastroenterology and Hepatology, Eskisehir Osmangazi University, Turkey.
  • Ömer Kiliç Department of Pediatric Infectious Disease, Eskisehir Osmangazi University, Turkey.
  • Evrim Ciftci Department of Pathology, Eskisehir Osmangazi University, Turkey.
  • Cigdem Sag Department of Pediatrics, Haydarpasa Numune Training Hospital, Istanbul, Turkey.
  • Ates Kara Pediatric Infectious Disease Unit, Hacettepe University, Ankara, Turkey.
  • Ener Cagri Dinleyici Pediatric Intensive Care Unit and Pediatric Infectious Disease, Eskisehir Osmangazi University, Turkey.

Abstract

Anogenital warts related to human papillomavirus (HPV) have been observed in children. Definition of the transmission mode, therapy, and follow-up for long term potential complications is important. A 27-month old girl was admitted with multiple pedunculated red-purple colored cauliflower-like lesions of 1.5 years duration. Clinical/histopathological and microbiological diagnosis was condyloma acuminate due to HPV type 16. After 12 weeks of imiquimod 5% cream application (pea-sized) overnight three times per week, the perianal warts had completely disappeared. The mode of transmission of HPV 16 in our case was probably horizontal, related to the sharing of common personal hygiene items in the women’s shelter. We report herein the case of an infant living in a women’s shelter with giant condyloma acuminata due to HPV 16, which was successfully treated with topical imiquimod therapy. This patient should be followed up for recurrence and potential malignant lesions related to HPV type 16.

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Published
2015-12-03
Section
Case Reports
Keywords:
Condyloma accuminata, human papillomavirus, HPV type 16, imiquimod, genital warts
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How to Cite
Dinleyici, M., Saracoglu, N., Eren, M., KiliçO., Ciftci, E., Sag, C., Kara, A., & Cagri Dinleyici, E. (2015). Giant condyloma acuminate due human papilloma virus type 16 in an infant successfully treated with topical imiquimod therapy. Dermatology Reports, 7(3). https://doi.org/10.4081/dr.2015.6134