Generalized mid dermal elastolysis

  • Maria João Cruz | mjmc@live.com.pt Department of Dermatology and Venereology, Hospital de São João, E.P.E., Porto, Portugal.
  • Ana Margarida Barros Department of Dermatology and Venereology, Hospital de São João, E.P.E., Porto, Portugal.
  • Filomena Azevedo Department of Dermatology and Venereology, Hospital de São João, E.P.E., Porto, Portugal.

Abstract

Mid-dermal elastolysis (MDE) is a rare skin disorder clinically characterized by the appearance of diffuse fine wrinkling, most often of the trunk and arms. This entity is distinguished from other elastolytic disorders by its characteristic selective loss of elastic fibers of the mid dermis. The aetiopathogenesis of the disease is still unclear as well as the effective treatment. Half of the cases described in the literature are associated with ultraviolet radiation exposure. Other reported triggering conditions such as urticaria, eczema and granuloma annulare suggests different eliciting inflammatory pathways. The authors describe the case of a 38-year-old woman who developed an urticarial eruption during months which progressed to generalized and severe fine wrinkling.

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Published
2011-12-01
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Issue
Section
Case Reports
Keywords:
mid dermal elastolysis, disorders of elactic fibers, elastophagocytosis
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How to Cite
Cruz, M. J., Barros, A. M., & Azevedo, F. (2011). Generalized mid dermal elastolysis. Dermatology Reports, 3(3), e52. https://doi.org/10.4081/dr.2011.e52