Psoralen plus ultraviolet A (PUVA) soaks and UVB TL01 treatment for chronic hand dermatoses

  • Lisbeth Jensen | l.jensen@ouh.regionsyddanmark.dk Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Denmark.
  • Anette Stensgaard Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Denmark.
  • Klaus Ejner Andersen Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Denmark.

Abstract

Chronic eczematous hand dermatoses with and without contact allergies are complex diseases, which makes it a challenge to select the best treatment and obtain an optimal patient experience and a satisfactory treatment result. The aim of this study was to evaluate retrospectively the clinical effect and patient experience of local treatment with psoralen plus ultraviolet A (PUVA) soaks and TL01 phototherapy for severe chronic hand dermatoses, and also to evaluate the quality of life for the subgroup of patients with allergic contact dermatitis including Compositae allergy. A retrospective evaluation of results for 94 consecutive patients having received a total of 121 treatment courses with local PUVA soaks or TL01 phototherapy for one of the following diagnoses (n=number of treatment courses): psoriasis (n=19), hyperkeratotic hand eczema (n=27), Pustulosis Palmoplantaris (PPP) (n=22), vesicular eczema (n=16), Compositae dermatitis (n=24), and allergic contact dermatitis (n=13). Moreover, semi-structured interviews with 6 selected patients having multiple contact allergies including Compositae allergy were used to evaluate quality of life. As a result, we found that PUVA soaks has good effect in patients with psoriasis and hyperkeratotic hand eczema and local phototherapy for chronic hand dermatoses is a useful treatment option in selected cases.

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Published
2012-02-07
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Keywords:
PUVA soaks, hand eczema, quality of life, compositae allergy
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How to Cite
Jensen, L., Stensgaard, A., & Andersen, K. E. (2012). Psoralen plus ultraviolet A (PUVA) soaks and UVB TL01 treatment for chronic hand dermatoses. Dermatology Reports, 4(1), e3. https://doi.org/10.4081/dr.2012.e3