Endocrinology Studies https://www.pagepress.org/journals/index.php/es <div><strong>Endocrinology Studies </strong>is an Open Access, peer-reviewed, online-only journal publishing research studies of endocrine-related systems as well as clinical aspects of endocrinology. Our journal publishes Original Research, Review Articles, Brief Reports, Case Reports, and Letters to the Editor.</div> PAGEPress Scientific Publications, Pavia, Italy en-US Endocrinology Studies 2038-9515 <p><strong>PAGEPress</strong> has chosen to apply the&nbsp;<a href="http://creativecommons.org/licenses/by-nc/4.0/" target="_blank" rel="noopener"><strong>Creative Commons Attribution NonCommercial 4.0 International License</strong></a>&nbsp;(CC BY-NC 4.0) to all manuscripts to be published.<br><br> An Open Access Publication is one that meets the following two conditions:</p> <ol> <li>the author(s) and copyright holder(s) grant(s) to all users a free, irrevocable, worldwide, perpetual right of access to, and a license to copy, use, distribute, transmit and display the work publicly and to make and distribute derivative works, in any digital medium for any responsible purpose, subject to proper attribution of authorship, as well as the right to make small numbers of printed copies for their personal use.</li> <li>a complete version of the work and all supplemental materials, including a copy of the permission as stated above, in a suitable standard electronic format is deposited immediately upon initial publication in at least one online repository that is supported by an academic institution, scholarly society, government agency, or other well-established organization that seeks to enable open access, unrestricted distribution, interoperability, and long-term archiving.</li> </ol> <p>Authors who publish with this journal agree to the following terms:</p> <ol> <li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</li> <li>Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li> <li>Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.</li> </ol> Recurrent deep vein thrombosis presenting in a patient with overt hyperthyroidism https://www.pagepress.org/journals/index.php/es/article/view/5096 We present a 35-year-old male patient who was diagnosed with hyperthyroidism and admitted to our hospital with complaints of pain and swelling over his left lower limb. Physical examination was suggestive of deep vein thrombosis of left lower limb. On further investigations and work up, he was found to have deep vein thrombosis of left lower limb involving left common femoral, popliteal and external iliac vein. Inherited causes of hypercoagulable states were ruled out after investigations. Serum homocystein levels were normal and serum antinuclear antibodies was negative. Factor VIII levels were raised. Two months later patient again presented with deep vein thrombosis of right lower limb. Factor VIII levels were out of range this time. Hyperthyroidism has been associated with hypercoagulability by various mechanisms but whether it is a true hypercoagulable state is not yet proven and reported in only few case reports. Pramila Dharmshaktu Abhilasha Garg Dinesh Dhanwal Naresh Gupta ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2014-02-06 2014-02-06 4 1 10.4081/es.2014.5096 Giant prolactinoma: the sound of silence https://www.pagepress.org/journals/index.php/es/article/view/5274 Prolactinomas typically present with oligoamenorrhea or galactorrhea in woman and headaches, visual changes or impotence in men with auditory symptoms being a rare presentation. We describe a case of a man who presented with bilateral hearing loss and was found to have a giant prolactinoma. Initial audiogram indicated an air-bone conduction gap suggesting a mixed sensorineural and conductive hearing loss. Measured prolactin was 3711.0 ng/mL and an a magnetic resonance revealed a 3.0×3.0×3.3 cm heterogeneously enhancing mass arising from the sella turcica compressing the left half of the optic chiasm. Several months after treatment, prolactin was 26 ng/mL and the patient reported marked improvement in his vision with mild improvement of his hearing. Although prolactinomas typically present with <em>classic</em> symptoms, one must be aware of unusual presentations. Further investigation is needed to access the correlation between prolactin and hearing loss, which may impact potential audiology screening for those with elevated prolactin. Shira R. Saul Maya P. Raghuwanshi ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 2014-06-17 2014-06-17 4 1 10.4081/es.2014.5274