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Desmoid abdominal tumour: a clinical case report and brief literature review

Irina Ivanova, Shahswar Arif, Dinko Dinev, Kalin Kalchev, Maria Atanassova, Iskren Kotzev
  • Shahswar Arif
    Medical University “Dr. Paraskev Stoyanov”, Varna, Bulgaria
  • Dinko Dinev
    University Hospital "St.Marina", Bulgaria
  • Kalin Kalchev
    University Hospital "St.Marina", Bulgaria
  • Maria Atanassova
    University Hospital "St.Marina", Bulgaria
  • Iskren Kotzev
    University Hospital "St.Marina", Bulgaria

Abstract

Desmoid tumours are unique mesenchymal neoplasm. They are able to spread to proximal tissues but tend not to metastasize. Our case presents a 66-year-old female referred for evaluation of the prominent, palpable mass located into the left abdomen. Imaging studies revealed a tumour up to 22 cm, extending below the diaphragm to the retroperitoneal and intra-abdominal cavity. Contrast enhanced ultrasound showed strong inhomogeneous arterial hyper-enhancement followed by persistent enhancement in a venous phase. Histology obtained with tru-cut needle biopsy established desmoid tumour, with overall proliferating activity (Ki-67 expression) of 20%. The lesion had been identified as sporadic and ‘unresectable’. During the patient’s follow-up a slow but continuous elevation of serum creatinine was registered eventually led to anuria, requiring emergent haemodialysis. The non-obstructing nephropathy is an unusual complication of the disease course, therefore we briefly reviewed the published data on abdominal desmoid tumours and critically analysed the relation with kidney injury.

Keywords

desmoid tumour; abdominal neoplasm; contrast enhanced ultrasound; nephropathy

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Submitted: 2016-06-26 13:09:40
Published: 2018-07-11 16:21:27
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Copyright (c) 2017 Irina Ivanova Ivanova, Shahswar Arif, Dinko Dinev, Kalin Kalchev, Maria Atanassova, Iskren Kotzev

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