Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient

  • Jin Yu Chieng | cjy511@yahoo.com Department of Medicine, Faculty of Medicine and Health Science, Universiti Putra Malaysia, Selangor, Malaysia. http://orcid.org/0000-0002-4704-5252
  • Yasotha Sugumaran Department of Medicine, Faculty of Medicine and Health Science, Universiti Putra Malaysia, Selangor, Malaysia.
  • Sellymiah Adzman Department of Pathology, Serdang Hospital, Selangor, Malaysia.
  • Pan Yan Department of Biomedical Science, The University of Nottingham, Semenyih, Malaysia.

Abstract

A 61-year-old Punjabi female patient presented with six months history of mild abdominal discomfort with bloody diarrhea. She did not have underlying chronic medical illness; she neither took steroid nor immunosuppressant. She was found anemic, thrombocytosis, and elevated C-reactive protein. Colonoscopy showed moderate left sided colitis, with histopathology evidence of ulcerative colitis (UC) with cytomegalovirus (CMV) infection. Her serum anti-CMV IgM antibody was detected. She was treated with intravenous ganciclovir, together with 5-ASA and tapering dose of steroid. Anemia was corrected. Subsequent clinic reviews and follow up endoscopies showed dramatically improvement. CMV colitis should be considered for the patients presenting with moderate to severe UC. Early prescription of antiviral would be beneficial in the treatment of flare of UC.

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Published
2017-12-13
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Issue
Section
Case Reports
Keywords:
Cytomegalovirus, ulcerative colitis, antiviral
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How to Cite
Chieng, J. Y., Sugumaran, Y., Adzman, S., & Yan, P. (2017). Synchronous cytomegalovirus infection in a newly diagnosed ulcerative colitis patient. Gastroenterology Insights, 8(1). https://doi.org/10.4081/gi.2017.6886