Idiopathic thrombocytopenic purpura in adults: the treatment paradigm

F Zaja; R Fanin

doi:10.4081/hmr.v3i3.573

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Idiopathic thrombocytopenic purpura (ITP) in adults is an acquired autoimmune disease characterized by increased platelet destruction, impaired megakaryocytes maturation with reduced platelets production, possible bleeding. The incidence is nearly 50 new cases per million people per year with a female prevalence particularly in younger.1 ITP exhibits a heterogeneous biologic and clinical behavior, frequently has an insidious onset with different severity of thrombocytopenia, chronic course and higher lifetime risk of fatality due to bleeding, mainly intracranial. 2

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Zaja, F., & Fanin, R. (2009). Idiopathic thrombocytopenic purpura in adults: the treatment paradigm. Hematology Meeting Reports (formerly Haematologica Reports), 3(3). https://doi.org/10.4081/hmr.v3i3.573

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