Unusual hematologic disease affecting Caucasian children traveling to Southeast Asia: acquired platelet dysfunction with eosinophilia

  • Anselm Chi-Wai Lee | anselm.cw.lee@gmail.com Children's Haematology and Cancer Centre, Mount Elizabeth Hospital, Singapore.

Abstract

An 11-year-old American boy was staying with his family in Indonesia. He presented with a 5-month history of recurrent bruises and ecchymosis. A clinical diagnosis of acquired platelet dysfunction with eosinophilia was made when his full blood counts showed hypereosinophilia (7.4×10 9/L) with normal platelet count and gray platelets under the microscope. The diagnosis was supported by abnormal platelet aggregation tests consistent with a storage pool disorder. The bleeding symptoms and eosinophilia resolved a month later with a full course of antihelminthic therapy. Hematologists should be aware of this unusual disease in travelers returning from the Southeast Asia.

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Published
2012-02-08
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Issue
Section
Case Reports
Keywords:
acquired platelet dysfunction, eosinophilia, hemorrhage, thrombocytopathy
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How to Cite
Lee, A. C.-W. (2012). Unusual hematologic disease affecting Caucasian children traveling to Southeast Asia: acquired platelet dysfunction with eosinophilia. Hematology Reports, 4(1), e5. https://doi.org/10.4081/hr.2012.e5