Hematological profile of sickle cell disease from South Gujarat, India

  • Sanjeev Shyam Rao Department of Pediatrics, Govt Medical College, Surat, Gujarat, India.
  • Jagdish Prasad Goyal | jpgoyal@rediffmail.com Department of Pediatrics, Govt Medical College, Surat, Gujarat, India.
  • SV Raghunath Department of Pediatrics, Govt Medical College, Surat, Gujarat, India.
  • Vijay B. Shah Department of Pediatrics, Govt Medical College, Surat, Gujarat, India.

Abstract

The aim of this study was to determine hematological profile of sickle cell disease (SCD) from Surat, South Gujarat, India. This prospective cross-sectional study was conducted in the Department of Pediatrics and Sickle Cell Anemia Laboratory, Faculty of Pathology, Government Medical College, Surat, India, between July 2009 and December 2010. Patients included in this study were in their steady state for a long period of time without any symptoms related to SCD or other diseases which could affect the hematological parameters. Venous blood of all patients was collected in ethylenediaminetetraacetic acid and hematological indices were measured. Thirty-three subjects homozygous in all were studied for their hematological parameters for sickle cell anemia. Moderate to severe anemia, low mean cell volume and high foetal hemoglobin dominate the hematological profile of SCD children.

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Published
2012-05-22
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Original Articles
Keywords:
Hematological profile, Sickle cell disease, Children, South Gujarat
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How to Cite
Rao, S. S., Goyal, J. P., Raghunath, S., & Shah, V. B. (2012). Hematological profile of sickle cell disease from South Gujarat, India. Hematology Reports, 4(2), e8. https://doi.org/10.4081/hr.2012.e8