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Allogeneic stem cell transplantation in acute myeloid leukemia

Natasha Ali, Salman Naseem Adil, Mohammad Usman Shaikh, Nehal Masood
  • Natasha Ali
    Department of Pathology and Microbiology, The Aga Khan University Hospital, Karachi, Pakistan | natasha.ali@aku.edu
  • Salman Naseem Adil
    Department of Pathology and Microbiology, The Aga Khan University Hospital, Karachi, Pakistan
  • Mohammad Usman Shaikh
    Department of Pathology and Microbiology, The Aga Khan University Hospital, Karachi, Pakistan
  • Nehal Masood
    Department of Medicine, The Aga Khan University Hospital, Karachi, Pakistan

Abstract

We report a case series of 12 patients with acute myeloid leukemia who underwent allogeneic stem cell transplant with a matched related donor. Male to female ratio was 1:1. The main complication post-transplant was graft-versus-host disease (n=7 patients). Transplant-related mortality involved one patient; cause of death was multi-organ failure. After a median follow up of 36.0±11.3 months, overall survival was 16%.

Keywords

allogeneic transplant, acute myeloid leukemia, outcome

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Submitted: 2012-08-19 08:55:42
Published: 2012-11-29 12:08:12
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