Cover Image

The prevalence of transfusion transmitted infections in ABO blood groups and Rh type system

Jitendra Singh Nigam, Savitri Singh, Viplesh Kaur, Sumit Giri, Ravi Prakash Kaushal
  • Jitendra Singh Nigam
    Department of Pathology, Saraswathi Institute of Medical Sciences, Anwarpur, India | nigamjs@gmail.com
  • Savitri Singh
    Department of Pathology, Saraswathi Institute of Medical Sciences, Anwarpur, India
  • Viplesh Kaur
    Department of Pathology, Saraswathi Institute of Medical Sciences, Anwarpur, India
  • Sumit Giri
    Department of Pathology, Saraswathi Institute of Medical Sciences, Anwarpur, India
  • Ravi Prakash Kaushal
    Department of Pathology, Saraswathi Institute of Medical Sciences, Anwarpur, India

Abstract

Screening of blood and blood products is important to reduce the risk of transfusion transmitted infections (TTIs). The transfusion of unscreened or inadequately screened blood and blood products are the major source of TTIs. The aim of this paper is to find out the prevalence of TTIs in ABO blood groups and Rh type system. A total of 4128 blood donors were screened from January 2010 to April 2014. Serological tests were performed for hepatitis B surface antigen (HBsAg), anti hepatitis C virus (Anti-HCV), anti HIV-1 and 2, venereal disease research laboratory test (VDRL) and malaria parasite (MP) antigen. In seroreactive donors, HBsAg, Anti-HCV, VDRL, MP antigen and anti HIV were positive in 40 cases, 26 cases, 19 cases, 6 cases and 2 cases, respectively. Highest percentage of HBsAg, Anti HCV, VDRL, MP antigen and anti HIV was observed in blood group A negative (2/50), O negative (1/66), B negative (1/91), AB positive (2/377) blood group respectively. In the present study, the total number of Rh-negative donors is lower when compared to Rh-positive blood donors, but Rh-negative blood donors show higher percentages of seroreactivity for TTIs. Larger scale studies at molecular level are required to improve the knowledge of this aspect.

Keywords

transfusion transmitted infections, blood products, ABO blood groups, Rh type system, India

Full Text:

PDF
HTML
Submitted: 2014-08-17 04:05:33
Published: 2014-12-04 08:27:55
Search for citations in Google Scholar
Related articles: Google Scholar
Abstract views:
1322

Views:
PDF
492
HTML
548

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM


Copyright (c)
 
© PAGEPress 2008-2018     -     PAGEPress is a registered trademark property of PAGEPress srl, Italy.     -     VAT: IT02125780185     •     Privacy