Kikuchi-Fujimoto disease involving retroperitoneal lymph nodes: An uncommon presentation

  • Jane Date Hon Department of Pathology and Hematology Division, University of Southern California Keck School of Medicine, Los Angeles, CA, United States.
  • Maria E. Vergara-Lluri Department of Pathology and Hematology Division, University of Southern California Keck School of Medicine, Los Angeles, CA, United States.
  • Imran Siddiqi Department of Pathology and Hematology Division, University of Southern California Keck School of Medicine, Los Angeles, CA, United States.
  • Christopher Foss Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, United States. https://orcid.org/0000-0002-1437-1799
  • Donald I. Feinstein Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, United States.
  • Russell K. Brynes | Brynes@med.usc.edu Department of Pathology and Hematology Division, University of Southern California Keck School of Medicine, Los Angeles, CA, United States.

Abstract

Kikuchi-Fujimoto disease is a self-limited disease of unknown etiology that is clinically defined by fevers accompanied by tender posterior cervical lymphadenopathy. It often presents acutely or sub-acutely, and due to its non-specific features, the differential diagnosis is broad and includes infectious, autoimmune, and malignant causes. Although cases of extra-cervical disease are not uncommon, involvement of retroperitoneal lymph nodes has only rarely been reported. Here, we describe a patient with Kikuchi-Fujimoto disease who presented with fever of unknown origin, abdominal pain, and enlarged hypermetabolic retroperitoneal lymph nodes.

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Published
2021-03-05
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Section
Case Reports
Keywords:
Kikuchi-Fujimoto disease, histiocytic necrotizing lymphadenitis, retroperitoneal lymph node
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How to Cite
Hon, J. D., Vergara-Lluri, M. E., Siddiqi, I., Foss, C., Feinstein, D. I., & Brynes, R. K. (2021). Kikuchi-Fujimoto disease involving retroperitoneal lymph nodes: An uncommon presentation. Hematology Reports, 13(2). https://doi.org/10.4081/hr.2021.9001