Cover Image

The immunohistochemical presence and distribution of ghrelin, apelin and their receptors in dog ovaries

Carolina Pirino, Margherita Maranesi, Angela Polisca, Alessandro Troisi, Cecilia Dall'Aglio
  • Margherita Maranesi
    Department of Veterinary Medicine, University of Perugia, Italy
  • Angela Polisca
    Department of Veterinary Medicine, University of Perugia, Italy
  • Alessandro Troisi
    Department of Veterinary Medicine, University of Perugia, Italy
  • Cecilia Dall'Aglio
    Department of Veterinary Medicine, University of Perugia, Italy

Abstract

The activity of ghrelin, apelin and their receptors has been correlated to the control of some infectious diseases, besides the hypothesis of their role in the control of some peripheral organs, among which ovaries. The aim of the present work was to highlight the presence and distribution of ghrelin, apelin and cognate receptors in the ovaries of pregnant bitches, by means of immunohistochemical techniques. Apelin, its receptor and the receptor of ghrelin were highlighted in the corpora lutea, with a particular localization in the cytoplasm of some luteal cells. Instead, a positive reaction for ghrelin was evident in the walls of small arteries in the connective tissue. These results allowed us to hypothesize that these molecules intervene in the control of ovaries in pregnant bitches, suggesting autocrine/paracrine mechanisms of regulation.

Keywords

apelin; ghrelin; pregnancy; canine; corpus luteum

Full Text:

PDF
HTML
Submitted: 2017-04-07 16:35:12
Published: 2017-09-15 11:04:48
Search for citations in Google Scholar
Related articles: Google Scholar
Abstract views:
209

Views:
PDF
65
HTML
43

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM




Copyright (c) 2017 Carolina Pirino, Margherita Maranesi, Angela Polisca, Alessandro Troisi, Cecilia Dall'Aglio

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
 
© PAGEPress 2008-2018     -     PAGEPress is a registered trademark property of PAGEPress srl, Italy.     -     VAT: IT02125780185     •     Privacy