Glioblastoma multiforme subterfuge as acute cerebral hemorrhage: A case report and literature review

  • Seidu A. Richard Graduate Training Centre, West China Hospital, Sichuan University, China; Department of Immunology, Jiangsu University, China; Department of Surgery, Volta Regional Hospital, Ho, Ghana.
  • Yunxia Ye Department of Pathology, West China Hospital, Sichuan University, China.
  • Hao Li Department of Neurosurgery, Post Graduate Training Centre, West China Hospital, Sichuan University, China.
  • Lu Ma | wchneuro@163.com Department of Neurosurgery, Post Graduate Training Centre, West China Hospital, Sichuan University, China.
  • Chao You Department of Neurosurgery, Post Graduate Training Centre, West China Hospital, Sichuan University, China.

Abstract

Hemorrhagic related Glioblastoma multiforme (GBM) are rare and characterizes with severe clinical scuffle. The etiology of this presentation although not well known is believed to be multifactorial. We present a case as well as review on the pathogenesis of evolution of the hematoma into ring enhancing features of GBM on imaging studies. We present a case of 28 years old man who suddenly went into coma for 9 hours preceded with seizures that latest for 10 minutes. He had no focal neurological signs. CT-Scans images indicated acute cerebral hemorrhage near the frontal horn of the left ventricle with brain edema about the hemorrhagic lesion and MRI done a week later revealed a cerebral ring enhancing lesion. The lesion was partially resected during surgery and immunohistochemical staining confirmed GBM (WHO, grade 4). The diagnosis of intratumoral hemorrhage in GBM was very challenging at the initial stages but with time the hematoma evolved into ring enhancing images typical of GBM. It’s not every intracranial hematoma that is of pure vascular origin.

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Published
2018-04-04
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Section
Case Reports
Keywords:
Glioblastoma multiforme, Hematoma, Hemorrhage, Seizures, Coagulopathy.
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How to Cite
Richard, S. A., Ye, Y., Li, H., Ma, L., & You, C. (2018). Glioblastoma multiforme subterfuge as acute cerebral hemorrhage: A case report and literature review. Neurology International, 10(1). https://doi.org/10.4081/ni.2018.7558