The basic science of bone marrow aspirate concentrate in chondral injuries

  • James Holton | holton1404@gmail.com Royal Orthopedic Hospital, The Woodlands, Birmingham, West Midlands, United Kingdom.
  • Mohamed Imam Royal Orthopedic Hospital, The Woodlands, Birmingham, West Midlands, UK; Department of Orthopedics, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
  • Jonathan Ward Royal Orthopedic Hospital, The Woodlands, Birmingham, West Midlands, United Kingdom.
  • Martyn Snow Royal Orthopedic Hospital, The Woodlands, Birmingham, West Midlands, United Kingdom.

Abstract

There has been great interest in bone marrow aspirate concentrate (BMAC) as a cost effective method in delivering mesenchymal stem cells (MSCs) to aid in the repair and regeneration of cartilage defects. Alongside MSCs, BMAC contains a range of growth factors and cytokines to support cell growth following injury. However, there is paucity of information relating to the basic science underlying BMAC and its exact biological role in supporting the growth and regeneration of chondrocytes. The focus of this review is the basic science underlying BMAC in relation to chondral damage and regeneration.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.
Published
2016-09-30
Info
Issue
Section
Reviews
Keywords:
Bone, marrow, aspirate, concentrate, cartilage
Statistics
  • Abstract views: 1188

  • PDF: 600
  • HTML: 261
How to Cite
Holton, J., Imam, M., Ward, J., & Snow, M. (2016). The basic science of bone marrow aspirate concentrate in chondral injuries. Orthopedic Reviews, 8(3). https://doi.org/10.4081/or.2016.6659