Two cases of esophageal eosinophilia: eosinophilic esophagitis or gastro-esophageal reflux disease?

  • Ozlem Yilmaz | drozlemyilmaz09@gmail.com Department of Pediatric Allergy and Asthma, Gazi University School of Medicine, Ankara, Turkey.
  • Hacer Ilbilge Ertoy Karagol Department of Pediatric Allergy and Asthma, Gazi University School of Medicine, Ankara, Turkey.
  • Erdem Topal Department of Pediatric Allergy and Asthma, Gazi University School of Medicine, Ankara, Turkey.
  • Aysel Unlusoy Aksu Department of Pediatric Gastroenterology, Gazi University School of Medicine, Ankara, Turkey.
  • Odul Egritas Department of Pediatric Gastroenterology, Gazi University School of Medicine, Ankara, Turkey.
  • Ipek Isık Gonul Department of Pathology, Gazi University School of Medicine, Ankara, Turkey.
  • Arzu Bakirtas Department of Pediatric Allergy and Asthma, Gazi University School of Medicine, Ankara, Turkey.

Abstract

Eosinophilic esophagitis (EoE) and gastro-esophageal reflux disease are among the major causes of isolated esophageal eosinophilia. Isolated esophageal eosinophilia meeting criteria for EoE may respond to proton pump inhibitor (PPI) treatment. This entity is termed proton pumps inhibitor responsive esophageal eosinophilia (PPI-REE). Gastro-esophageal reflux is thought to comprise a subgroup of patients with PPI-REE. According to the latest guidelines, PPI responsiveness distinguishes people with PPI-REE from patients having EoE (non-responders). In this report, two unusual cases with findings belonging to both EoE and PPI-REE are discussed with known and unknown facts.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.
Published
2014-06-16
Info
Issue
Section
Case Reports & Letters
Keywords:
children, eosinophils, esophagitis, proton pumps inhibitors
Statistics
  • Abstract views: 1539

  • PDF: 601
  • HTML: 195
How to Cite
Yilmaz, O., Ertoy Karagol, H. I., Topal, E., Unlusoy Aksu, A., Egritas, O., Gonul, I. I., & Bakirtas, A. (2014). Two cases of esophageal eosinophilia: eosinophilic esophagitis or gastro-esophageal reflux disease?. Pediatric Reports, 6(2). https://doi.org/10.4081/pr.2014.5160