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FOCUS: SARS-CoV-2, “common cold” coronaviruses’ cross-reactivity and “herd immunity”: The razor of Ockham (1285-1347)?

2020-05-29

After the rapid spread of coronavirus-19 infectious disease (COVID-19) worldwide between February and April 2020, with a total of 5,267,419 confirmed cases and 341,155 deaths as of May 25, 2020, in the last weeks we are observing a decrease in new infections in European countries, and the confirmed cases are not as severe as in the past, so much so that the number of patients transferred to intensive care for the worsening of the systemic and pulmonary disease is dramatically decreasing [...]

Infectious Disease Reports https://doi.org/10.4081/idr.2020.8647
Nicola Petrosillo, National Institute for Infectious Diseases “L. Spallanzani”, IRCCS, Rome, Italy.
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How the COVID-19 infection tsunami revolutionized the work of respiratory physiotherapists: an experience from Northern Italy

2020-05-20

Due to COVID-19 outbreak, to lighten the burden of acute and critical care hospitals, some respiratory rehabilitation departments have been used to host patients with COVID-19 in the post-acute phase. This new and unexpected situation required a change of roles and scheduling of the rehabilitation teams. In this manuscript we describe the unexpected and urgent organizational change of the Cardio-Pulmonary Rehabilitation (CPR) service during the COVID-19 emergency in a Northern Italian rehabilitation hospital, focusing on the Respiratory Physiotherapists’ (RPTs) role.

Monaldi Archives for Chest Disease https://doi.org/10.4081/monaldi.2020.1085
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Ambroxol for the treatment of children with acute and chronic respiratory diseases: an overview of efficacy and safety

2020-05-19

Ambroxol (2-amino-3,5-dibromo-N-[trans-4-hydroxycyclohexyl]benzylamine), an over-thecounter product, is a mucoactive agent and has been used widely to treat both acute and chronic respiratory diseases since 1978. This review aims to provide an overview of the clinical evidence available on the use of ambroxol in children with acute and chronic respiratory diseases. Data for this review were obtained from both published and unpublished clinical studies, and real-world evidence studies. Although conducted prior to the introduction of Good Clinical Practice (GCP), these studies, representing almost 1,300 pediatric patients, report strong clinical outcomes following the use of ambroxol in pediatric patients. Furthermore, ....

Multidisciplinary Respiratory Medicine https://doi.org/10.4081/mrm.2020.511
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Evaluation of serum levels of iron, total iron binding capacity, transferrin saturation and ferritin in chronic kidney disease patients vs. control group

2020-05-18

The magnitude of chronic renal disease is enormous, as the prevalence of kidney failure is rising. Anaemia is a common complication of chronic kidney disease (CKD) that develops early in its course and becomes increasingly severe as the disease progresses. The aim is to evaluate the serum level of iron, Total Iron Binding Capacity (TIBC), transferrin saturation and ferritin in chronic kidney disease population in Zaria and control subjects.

https://doi.org/10.4081/aamr.2019.101
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COVID-19: a review

2020-05-15

The enduring epidemic outbreak which started in Wuhan city of China, in December 2019 caused by the 2019 novel coronavirus (COVID- 19) or the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has created a dangerous and deadly Public Health disaster of International apprehension, with cases confirmed in several countries. This novel community health trouble is frightening the universe with clinical, psychological, emotional, collapse of health system and economical slowdown in each and every part of the world infecting nearly 200 countries... Monaldi Archives for Chest Disease https://doi.org/10.4081/monaldi.2020.1298
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COVID-19 and clinical mimics. Correct diagnosis is the key to appropriate therapy

2020-05-07

#COVIDー19 and clinical mimics. Challenges faced while approaching any case of shortness of breath, or other common upper respiratory symptoms during the current #COVID19 #pandemic era.

Monaldi Archives of Chest Disease https://doi.org/10.4081/monaldi.2020.1327

As of 29 April 2020, across the globe, there are 3,216,353 confirmed Coronavirus disease 2019 (COVID-19 disease) with 227,894 deaths. The health care infrastructure of most of the countries is overwhelmed due to the gigantic upsurge of the new cases within a short time period. Most of the beds in the regular wards and critical care units are currently occupied by either people under investigation (PUI) or COVID-19 confirmed cases. We hereby discuss the challenges faced while approaching any case of shortness of breath, or other common upper respiratory symptoms during the current COVID-19 pandemic era.
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Comparison of bortezomib-cyclophosphamide-dexamethasone versus bortezomib-dexamethasone based regimens in newly diagnosed multiple myeloma patients

2020-05-07

Hematology Reports https://doi.org/10.4081/hr.2020.8267

The treatment landscape and clinical outcome of multiple myeloma (MM) patients have changed in the last decades, with an improved median survival of 8-10 years. This study aimed to evaluate the bortezomib, cyclophosphamide and dexamethasone (VCD) regimen versus bortezomib and dexamethasone (VD) regimen in patients with newly diagnosed MM. This study has been performed in a retrospective manner. One hundred and three patients with newly diagnosed MM who received chemotherapy at our tertiary care center between the years of 2009 and 2018 were evaluated. A total of 103 patients were included. The 5-year overall survival (OS) for patients who received VD regimen and patients who received VCD regimen were 75% and 83%, respectively. The OS for VD patients was 113.1±12.5 versus 122.2±9.5 months for VCD patients with no statistically significant difference (P=0.47). The 5- year PFS (progression free survival) for patients who received VD regimen and patients who received VCD regimen were 66% and 75%, respectively. The PFS for VCD patients was higher than the PFS for VD patients (67.1±7.4 versus 97.7±13.4 months), but no statistically significant difference was observed (P=0.59). Relapse rate (P=0.002) and mortality rate (P=0.01) were higher in VD group than VCD group and they were statistically significant. The OS and PFS were clinically longer in patients receiving VCD regimen than in patients receiving VD regimen, although not statistically significant. Cyclophosphamide should be given to patients at physician discretion and depending on patient’s frailty function.

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Critical shoulder angle is intrinsically associated with the development of degenerative shoulder diseases: A systematic review

2020-05-06

Aim of this study was to investigate the potential influence of Critical Shoulder Angle (CSA) as a predisposing factor for the development of degenerative full-thickness rotator cuff tears (DRCT) or primary glenohumeral osteoarthritis (PGOA). A systematic review of the Pubmed, Scopus, Mendeley, ScienceDirect and the Cochrane Central Register of Controlled Trials online databases was performed for literature regarding CSA and its association with DRCT and PGOA. In order to evaluate solely the relationship between CSA as a predisposing factor for the development of the aforementioned degenerative shoulder diseases (DSDs), we precluded any study in which traumatic cases were not clearly excluded. Our search strategy identified 289 studies in total, nine of which were eligible for inclusion based on our pre-established criteria. Quality assessment contacted using the Newcastle Ottawa Scale for case-control studies. There were a total of 998 patients with DRCT and 285 patients with PGOA. The control groups consisted of a total of 538 patients. The mean CSA ranged from 33.9° to 41.01° for the DRCT group, from 27.3° to 29.8° for the PGOA group and from 30.2° to 37.28° for the control group. All studies reported statistically significant differences between the DRCT and PGOA groups and the respective control groups. Our study results showed that there is moderate evidence in the literature supporting an intrinsic role of CSA in the development of DSDs. Level of evidence: IV. Systematic review of diagnostic studies, Level II-IV.

Read at https://doi.org/10.4081/or.2020.8457
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Prostate-specific antigen velocity in diagnosis and prognosis of prostate cancer - a systematic review

2020-05-04

Prostate-specific antigen velocity (PSAV) is widely used to detect PC and predict its progression. In this study, we qualitatively synthesized the currently available evidence from published studies regarding the PSAV role in PC. Electronic databases were searched to find relevant articles published until January 2019. Inclusion and exclusion criteria were applied to identify related papers. Eventually, data extraction followed by evidence synthesis was conducted. Full-text screening resulted in 42 included studies. Multiple definitions and intervals were used for PSAV calculation across studies. Go to https://doi.org/10.4081/oncol.2020.449
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What did COVID-19 do to the organization of Italian rheumatology? The examples of Luigi Sacco University Hospital and the Local Health district of ATS Sardegna: the two faces of the same coin

2020-04-28

Leading scientists and influential professional societies have been warning of the dangers of emerging infections and the threat of a global pandemic for years, but nobody imagined that the new decade would open with the most significant global public health challenge of our lives.

[http://beyond-rheumatology.org/index.php/br/article/view/37]
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COVID-19 and renal disease in elderly patients

2020-04-27

The pandemic blast of COVID-19 uncovered well known weakness of financial chain and put our economic organizations facing off dramatic consequences if new strategies will not be developed to adapt health-care on detailed sub-groups of patients.
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The Multidimensional Prognostic Index (MPI) for the prognostic stratification of hospitalized older patients with COVID-19: a prospective multicenter observational cohort study. Objectives, study design and expected outcomes (MPI_COVID-19)

2020-04-27

The emergent coronavirus-19 disease (COVID-19) pandemic posed and still poses serious issues in the management of the inpatients and in the resource allocation, in particular for those patients requiring Intensive Care Unit (ICU) management. Epidemiological data clearly suggest that multimorbid older patients have the poorest prognosis. However, it is conceivable that age and number of comorbidities alone do not reflect the real condition and the expected prognosis of the patients affected by COVID-19.

https://doi.org/10.4081/gc.2020.9038
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Hospital care in Departments defined as Covid-free: A proposal for a safe hospitalization protecting healthcare professionals and patients not affected by Covid 19

2020-04-24

The Archives of Italian Urology and Andrology publishes papers dealing with the urological, nephrological and andrological sciences. Original Articles on both clinical and research fields, Reviews, Editorials, Case Reports, Abstracts from papers published elsewhere, Book Reviews, Congress Proceedings can be published.

The Covid-19 pandemic influenced the normal course of clinical practice leading to significant delays in the delivery of healthcare services for patients non affected by Covid 19. In the near future, it will be crucial to identify facilities capable of providing health care in compliance with the safety of healthcare professionals, administrative staff and patients. All the staff involved in the project of a Covid-free hospital should be subjected to a diagnostic swab for Covid-19 before the beginning of healthcare activity and then periodically in order to avoid the risk of contamination of patients during the process of care.
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Changing Emergency Department and hospital organization in response to a changing epidemic

2020-04-20

#Covid_19 epidemic requires activation of an Internal #Emergency Preparedness Plan which a greater complexity than a usual one. Read here the paper from the Academy of Emergency Medicine and Care, Italy.

Coen, D., Paolillo, C., Cavazza, M., Carvellin, G., Bellone, A., Perlini, S., & Casagranda, I. (2020). Changing Emergency Department and hospital organization in response to a changing epidemic. Emergency Care Journal, 16(1). https://pagepressjournals.org/index.php/ecj/article/view/8969
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COVID-19 pandemic: what consequences for cardiac rehabilitation?

2020-04-17

The ongoing COVID-19 pandemic spreading all around the world has stressed over its capabilities and determined profound changes in the health systems in all countries and has caused hundreds of thousand deaths. Health professionals have been called to a tremendous effort to deal with this emergency, often contaminating or succumbing themselves to the disease.
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Oxygen-ozone immunoceutical therapy in COVID-19 outbreak: facts and figures

2020-04-10

The problems related to the approach to the outbreak of COVID-19 in the world require that all possible effective treatment options be explored. The clinical criterion of the researcher is not to refuse a priori, but to verify and evaluate the proposals that are made. Italian Society of Oxygen Ozone Therapy (SIOOT) proposed to the Italian ISS (Italian Institute of Health) to use oxygen ozone therapy (O2O3) in patients with COVID-19. (...)

https://doi.org/10.4081/ozone.2020.9014
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Respiratory physiotherapy in patients with COVID-19 infection in acute setting: a Position Paper of the Italian Association of Respiratory Physiotherapists (ARIR)

2020-04-10

On February 2020, Italy, especially the northern regions, was hit by an epidemic of the new SARS-Cov-2 coronavirus that spread from China between December 2019 and January 2020.

https://doi.org/10.4081/monaldi.2020.1285
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Recommendations for COVID-19 Clinical Management

2020-03-17

Recommendations for COVID-19 Clinical Management from the National Institute for the Infectious Diseases “L. Spallanzani”, IRCCS, Rome, Italy.
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Launching Annals of Clinical and Biomedical Research

2020-03-05

The scope of Annals of Clinical and Biomedical Research will include both basic sciences and clinical medicine- internal medicine, surgery, obstetrics and gynecology, pediatrics, psychiatry and clinical psychology.
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Launching Ricerca Psicoanalitica

2020-01-24

Ricerca Psicoanalitica is a member of the Council of Editors of Psychoanalytic Journals and has been for over two decades the journal of relations in psychoanalysis in Italy.
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Launching Multidisciplinary Respiratory Medicine

2020-01-24

Multidisciplinary Respiratory Medicine is the official journal of the Italian Respiratory Society - Società Italiana di Pneumologia (IRS/SIP).
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PAGEPress Publications signs Declaration on Research Assessment (DORA)

2019-11-11

PAGEPress has signed the San Francisco Declaration on Research Assessment (DORA).
DORA is a worldwide initiative covering all scholarly disciplines which recognizes the need to improve the ways in which the outputs of scholarly research are evaluated and seeks to develop and promote best practice. To date it has been signed by over 1500 organizations and around 15000 individuals.
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Launching Infectious Diseases and Herbal Medicine

2019-09-04

Infectious Diseases and Herbal Medicine (IDHM) is an international, Open Access, peer-reviewed, authoritative journal providing basic and applied research.
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Launching Beyond Rheumatology

2019-09-04

Beyond Rheumatology is an international, open access, peer-reviewed journal of CReI (Collegio dei Reumatologi Italiani), committed to publishing new discoveries on diagnostic, prognostic, clinical and therapeutic topics about rheumatism and allied conditions.
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Giornale Italiano di Endodonzia: a new life begins!

2019-09-03

The Giornale Italiano di Endodonzia was founded in 1987 and is the official journal of the Italian Society of Endodontics (SIE). It is a peer-reviewed journal publishing original articles on clinical research and/or clinical methodology, case reports related to Endodontics. The Journal evaluates also contributes in restorative dentistry, dental traumatology, experimental pathophysiology, pharmacology and microbiology dealing with Endodontics. The Giornale Italiano di Endodonzia is indexed in Scopus, Science Direct, SCImago, Embase, Google Scholar, Academic Search EBSCO, OCLC.
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