Comparative analysis of different hydrogels for the bioprinting of 3D in vitro skeletal muscle models


https://doi.org/10.4081/bse.146
Vol. 2 No. 1 (2021)
Published: 29 September 2021
3D bioprinting, tissue engineering, hydrogels, regenerative medicine, C2C12 myoblast cell line
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Authors

  • Flaminia Aliberti
    flaminia.aliberti01@universitadipavia.it
    Center for Inherited Cardiovascular Diseases, Transplant Research Area, Fondazione IRCCS Policlinico San Matteo, Pavia; Department of Public Health, Experimental Medicine and Forensic, Center for Health Technologies (C.H.T.)-Human Anatomy Unit, University of Pavia, Pavia, Italy.
  • Lorenza Rinvenuto Department of Public Health, Experimental Medicine and Forensic, Center for Health Technologies (C.H.T.)-Human Anatomy Unit, University of Pavia, Pavia, Italy.
  • Giada Loi Department of Civil Engineering, University of Pavia, Pavia, Italy.
  • Laura Benedetti Department of Public Health, Experimental Medicine and Forensic, Center for Health Technologies (C.H.T.)-Human Anatomy Unit, University of Pavia, Pavia;, Italy.
  • Franca Scocozza Department of Civil Engineering, University of Pavia, Pavia, Italy.
  • Flavio Lorenzo Ronzoni Department of Biomedical Sciences, Humanitas University, Rozzano, Italy.
  • Maurilio Sampaolesi Department of Public Health, Experimental Medicine and Forensic, Center for Health Technologies (C.H.T.)-Human Anatomy Unit, University of Pavia, Pavia, Italy.
  • Gabriella Cusella Department of Public Health, Experimental Medicine and Forensic, Center for Health Technologies (C.H.T.)-Human Anatomy Unit, University of Pavia, Pavia, Italy.
  • Michele Conti Department of Civil Engineering, University of Pavia, Pavia, Italy.
  • Gabriele Ceccarelli Department of Public Health, Experimental Medicine and Forensic, Center for Health Technologies (C.H.T.)-Human Anatomy Unit, University of Pavia, Pavia, Italy.

In this study we demonstrated an application of 3D Bioprinting using different commercially available hydrogels (CELLINK AB, Sweden) with the aim to identify the most suitable biomaterial for the proliferation and differentiation of murine muscle cells (C2C12).


Aliberti, F., Rinvenuto, L., Loi, G., Benedetti, L., Scocozza, F., Ronzoni, F. L., Sampaolesi, M., Cusella, G., Conti, M., & Ceccarelli, G. (2021). Comparative analysis of different hydrogels for the bioprinting of 3D <em>in vitro</em> skeletal muscle models. Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.146

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