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Giant virilizing adrenocortical carcinoma in a girl presenting with mutism

Huseyin Demirbilek, Serhan Kupeli, Mehmet Nuri Ozbek, Ahmet Baran, Murat Kemal Cigdem, Selver Ozekinci
  • Huseyin Demirbilek
    Diyarbakir Children Diseases Hospital, Pediatric Endocrinology, Diyarbakir, Turkey |
  • Serhan Kupeli
    Diyarbakir Children Diseases Hospital, Pediatric Oncology, Diyarbakir, Turkey
  • Mehmet Nuri Ozbek
    Diyarbakir Children Diseases Hospital, Pediatric Endocrinology, Diyarbakir, Turkey
  • Ahmet Baran
    Diyarbakir Children Diseases Hospital,Radiology, Diyarbakir,
  • Murat Kemal Cigdem
    Dicle University, Pediatric Surgery, Diyarbakir, Turkey
  • Selver Ozekinci
    Dicle University, Pathology, Diyarbakir, Turkey


Adrenocortical tumors (ACT) are rare tumors of childhood. There are some difficulties in classification of pediatric ACT as adenoma or carcinoma. Prognostic characteristics as well as treatment choices are controversial. In general virilizing ACT are presenting at earlier age than non-functional tumors. Here we presented an early presented, delayed diagnosed giant virilizing adrenocortical tumor in a girl presented with mutism. Present case is interesting both in complaints at the presentation and the nature of tumor biology. Based on previously reported prognostic criteria present case had borderline characteristics and treatment option was only total resection of the tumor without adjuvant chemotherapy.

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Submitted: 2011-05-26 20:49:23
Published: 2011-08-01 09:12:17
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