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Current evidence of antifungal prophylaxis and therapy in pediatric patients

Mareva Giacchino, Giuseppe Maria Milano, Francesca Carraro, Stefania Bezzio, Anna Pegoraro, Franco Aversa, Simone Cesaro
  • Giuseppe Maria Milano
    Affiliation not present
  • Francesca Carraro
    Affiliation not present
  • Stefania Bezzio
    Affiliation not present
  • Anna Pegoraro
    Affiliation not present
  • Franco Aversa
    Affiliation not present
  • Simone Cesaro
    Affiliation not present

Abstract

Invasive fungal infections (IFI) are frequent in pediatric patients with haematological malignancies during induction therapy and relapse and with advanced stage or relapsing solid tumours. Although the incidence of IFI is low mortality rates are high. This review is designed to help orientate paediatric oncologists in appropriate choice of anti-fungal agents for children. Indications for prophylaxis, empirical and pre-emptive therapy are given. The efficacy and indications for use of anti-fungal agents to treat IFI in children are presented.

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Submitted: 2010-12-13 14:51:25
Published: 2011-03-10 10:34:05
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