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DOI: http://dx.doi.org/10.4081/rt.2010.e20

Angiomatoid fibrous histiocytoma in a 25-year-old male

Aaron Scott Mansfield, Brenda Larson, Scott L. Stafford, Thomas C. Shives, Michael G. Haddock, David Dingli


Angiomatoid fibrous histiocytoma (AFH) is a rare disease that is often misdiagnosed initially. Patients can present with a clinical picture concerning for other diseases, and pathologic review is not always revealing. Molecular diagnostics are increasingly being utilized to detect gene fusions characteristic for AFH. Surgery remains the mainstay of management, and can effectively control local recurrences and metastases. Herein we describe a case report of a 25-year-old gentleman whose presentation was concerning for lymphoma. Subsequently we review of the relevant literature.


Angiomatoid fibrous histiocytoma, soft tissue tumor

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Submitted: 2010-01-05 21:16:33
Published: 2010-03-24 16:03:52
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