Hemostatic changes in normal pregnancy


Published: June 5, 2009
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Normal pregnancy is accompanied by changes in the coagulation and fibrinolytic systems. These include a decrease in platelet count, increases in a number of clotting factors, a decrease in protein S levels, a significant fall in the activity of activated protein C and inhibition of fibrinolysis. These changes may be important for reducing intrapartum blood loss, but they determine an increased risk of thromboembolism during pregnancy and puerperium.

Supporting Agencies


Prisco, D., Ciuti, G., & Falciani, M. (2009). Hemostatic changes in normal pregnancy. Hematology Meeting Reports (formerly Haematologica Reports), 1(10). https://doi.org/10.4081/hmr.v1i10.340

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