Auto and allotransplant in cutaneous T-cell lymphomas

Cutaneous T-Cell lymphomas (CTCL), a very heterogeneous group of disease-entities, represent 2.2% of all lymphomas, with an incidence of about 0.30/100,000/year, which increases with age. They are more frequent in males than in females (ratio 2.2:1) and in black than in white populations. Among CTCL, mycosis fungoides (MF) represents the prototype and the most common form. The natural history of MF is usually indolent, even though, over time, a stepwise cutaneous evolution is usually observed. Hence, a clinical picture characterized by erythematous macular eruptions can be supplanted by sequential appearances of isolated or generalized patches, plaques and tumours, which correspond to different histopathological stages. In consequence, the prognosis of pati