Defining The Translocation Mechanism In Therapy-Related Acute Promyelocytic Leukaemia

Published: June 16, 2009
Abstract Views: 206
Untitled: 168
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Acute myeloid leukaemia (AML) occurring in children and younger adults is commonly associated with reciprocal balanced chromosomal translocations, which lead to the formation of chimaeric proteins that play a key role in mediating the leukaemic phenotype (reviewed 1).

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Mistry, A. R., Mays, A., Mason, A., Reiter, A., Wiemels, J. W., Segal, M., Solomon, E., Chomienne, C., Fenaux, P., Felix, C., & Grimwade, D. (2009). Defining The Translocation Mechanism In Therapy-Related Acute Promyelocytic Leukaemia. Hematology Meeting Reports (formerly Haematologica Reports), 2(15). https://doi.org/10.4081/hmr.v2i15.602