Endocrinology Studies 2015-09-10T15:43:20+02:00 Emanuela Fusinato Open Journal Systems <div><strong>Endocrinology Studies </strong>is an Open Access, peer-reviewed, online-only journal publishing research studies of endocrine-related systems as well as clinical aspects of endocrinology. Our journal publishes Original Research, Review Articles, Brief Reports, Case Reports, and Letters to the Editor.</div> Recurrent deep vein thrombosis presenting in a patient with overt hyperthyroidism 2015-09-10T15:43:20+02:00 Pramila Dharmshaktu Abhilasha Garg Dinesh Dhanwal Naresh Gupta We present a 35-year-old male patient who was diagnosed with hyperthyroidism and admitted to our hospital with complaints of pain and swelling over his left lower limb. Physical examination was suggestive of deep vein thrombosis of left lower limb. On further investigations and work up, he was found to have deep vein thrombosis of left lower limb involving left common femoral, popliteal and external iliac vein. Inherited causes of hypercoagulable states were ruled out after investigations. Serum homocystein levels were normal and serum antinuclear antibodies was negative. Factor VIII levels were raised. Two months later patient again presented with deep vein thrombosis of right lower limb. Factor VIII levels were out of range this time. Hyperthyroidism has been associated with hypercoagulability by various mechanisms but whether it is a true hypercoagulable state is not yet proven and reported in only few case reports. 2014-02-06T18:08:50+01:00 ##submission.copyrightStatement## Giant prolactinoma: the sound of silence 2015-09-10T15:43:20+02:00 Shira R. Saul Maya P. Raghuwanshi Prolactinomas typically present with oligoamenorrhea or galactorrhea in woman and headaches, visual changes or impotence in men with auditory symptoms being a rare presentation. We describe a case of a man who presented with bilateral hearing loss and was found to have a giant prolactinoma. Initial audiogram indicated an air-bone conduction gap suggesting a mixed sensorineural and conductive hearing loss. Measured prolactin was 3711.0 ng/mL and an a magnetic resonance revealed a 3.0×3.0×3.3 cm heterogeneously enhancing mass arising from the sella turcica compressing the left half of the optic chiasm. Several months after treatment, prolactin was 26 ng/mL and the patient reported marked improvement in his vision with mild improvement of his hearing. Although prolactinomas typically present with <em>classic</em> symptoms, one must be aware of unusual presentations. Further investigation is needed to access the correlation between prolactin and hearing loss, which may impact potential audiology screening for those with elevated prolactin. 2014-06-17T17:55:41+02:00 ##submission.copyrightStatement##