Hemophagocytic lymphohistiocytosis in newborn and infants


https://doi.org/10.4081/hmr.v2i10.463
Vol. 2 No. 10: Vth International Neonatal Hematology and Immunology Meeting
Published: June 9, 2009
Abstract Views: 125
PDF: 216
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Familial hemophagocytic lymphohistiocytosis (FHL or HLH) is a rare disorder of early infancy with autosomal recessive inheritance and usually fatal outcome. Its frequency has been estimated around 1 in 50.000 children/year in Sweden. The disease was initially reported in 1952 by a pediatrician who already described most of its prominent features, i.e. propensity to fatal outcome following an infectious disease, a lymphoma-like picture, peculiar observation of hypertriglyceridemia and hemophagocytosis. The familial recurrence of this disease clearly pointed to a genetic defect.

Supporting Agencies


Aricò, M. (2009). Hemophagocytic lymphohistiocytosis in newborn and infants. Hematology Meeting Reports (formerly Haematologica Reports), 2(10). https://doi.org/10.4081/hmr.v2i10.463
Authors who publish with this journal agree to the following terms: Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

Downloads

Citations

Crossref
Scopus
Google Scholar
Europe PMC