Fecal microbiota transplantation: the state of the art

  • Stefano Di Bella | stefano932@gmail.com National Institute for Infectious Diseases L. Spallanzani, Rome, Italy.
  • Cecilia Drapeau Department of Medical Microbiology, King’s College Hospital, London, United Kingdom.
  • Esther García-Almodóvar Department of Internal Medicine, Son Espases University Hospital, Palma of Majorca, Spain.
  • Nicola Petrosillo National Institute for Infectious Diseases L. Spallanzani, Rome, Italy.

Abstract

Clostridium difficile infection (CDI) is an emerging problem in terms of incidence, morbidity and mortality. Currently available treatment options are not always effective, especially in cases of recurrent/refractory or complicated CDI. The gut microbiota transplantation is a technique that has been sporadically practiced since the ‘50s, but its clinical efficacy has only recently been supported by scientific evidence. In the present article, we report the pathophysiological basis and the clinical indications of this technique that, in light of its low cost, and proven efficacy and safety, is likely to become part of the management guidelines of difficult cases of CDI in the near future.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.
Published
2013-11-27
Info
Issue
Section
Reviews
Keywords:
Clostridium difficile infection, microbiota transplantation
Statistics
  • Abstract views: 3716

  • PDF: 545
  • HTML: 256
How to Cite
Di Bella, S., Drapeau, C., García-AlmodóvarE., & Petrosillo, N. (2013). Fecal microbiota transplantation: the state of the art. Infectious Disease Reports, 5(2), e13. https://doi.org/10.4081/idr.2013.e13