Erysipelothrix rhusiopathiae bacteremia without endocarditis: rapid identification from positive blood culture by MALDI-TOF mass spectrometry. A case report and literature review

  • Luigi Principe Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy.
  • Silvia Bracco Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy.
  • Carola Mauri Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy.
  • Silvia Tonolo Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy.
  • Beatrice Pini Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy.
  • Francesco Luzzaro | f.luzzaro@ospedale.lecco.it Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy. http://orcid.org/0000-0002-8275-8389

Abstract

Erysipelothrix rhusiopathiae is a Gram-positive bacillus that is infrequently responsible for infections in humans. Three forms have been classified: a localized cutaneous form (erysipeloid) caused by traumatic penetration of E. rhusiopathiae, a generalized cutaneous form and a septicemic form. The latter type of disease has been previously associated with a high incidence of endocarditis. Here we report a case of E. rhusiopathiae bacteremia in a 74- year-old man, probably started from an erysipeloid form, in which endocarditis did not develop. This case presents some particular and uncommon features: i) no correlation with animal source; ii) correlation between bacteremia and erysipeloid lesion; iii) absence of endocarditis. MALDI-TOF mass spectrometry allowed to obtain a rapid identification (within 4 hours from bottle positivity) of E. rhusiopathiae. Together with direct antimicrobial susceptibility testing, this approach could improve the rate of appropriate therapy for bloodstream infections due to this fastidious pathogen.

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Published
2016-03-21
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Section
Case Reports
Keywords:
Erysipelas, skin and soft tissue infections, antimicrobial treatment, empirical therapy
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How to Cite
Principe, L., Bracco, S., Mauri, C., Tonolo, S., Pini, B., & Luzzaro, F. (2016). Erysipelothrix rhusiopathiae bacteremia without endocarditis: rapid identification from positive blood culture by MALDI-TOF mass spectrometry. A case report and literature review. Infectious Disease Reports, 8(1). https://doi.org/10.4081/idr.2016.6368