Hip and knee replacement in patients with ochronosis: Clinical experience and literature review

  • Cesare Meschini Department of Orthopedics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Università Cattolica del Sacro Cuore, Rome, Italy.
  • Michele Cauteruccio Department of Orthopedics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Università Cattolica del Sacro Cuore, Rome, Italy.
  • Maria Serena Oliva Department of Orthopedics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Università Cattolica del Sacro Cuore, Rome, Italy.
  • Giuseppe Sircana Department of Orthopedics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Università Cattolica del Sacro Cuore, Rome, Italy.
  • Raffaele Vitiello Department of Orthopedics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Università Cattolica del Sacro Cuore, Rome, Italy.
  • Giuseppe Rovere | rovere292@hotmail.com Department of Orthopedics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Università Cattolica del Sacro Cuore, Rome, Italy.
  • Francesco Muratori Department of Oncologic and Reconstructive Orthopedic Surgery, Azienda Ospedaliera Universitaria Careggi, Florence, Italy.
  • Giulio Maccauro Department of Orthopedics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Università Cattolica del Sacro Cuore, Rome, Italy.
  • Antonio Ziranu Department of Orthopedics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Università Cattolica del Sacro Cuore, Rome, Italy.

Abstract

Patients with alkaptonuria can present ochronotic degenerative arthropathy due to the accumulation of pigments in the cartilages. Ochronotic arthropathy initially affects the spine, then there is the involvement of the other large joints, with greater frequency of the knees. In this article we will present two patients with alkaptonuria who have been effectively treated with knee and hip replacement, comparing our experience with what is available in the literature.

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Published
2020-06-26
Keywords:
Ochronosis, alkaptonuria, hip and knee replacement.
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How to Cite
Meschini, C., Cauteruccio, M., Oliva, M. S., Sircana, G., Vitiello, R., Rovere, G., Muratori, F., Maccauro, G., & Ziranu, A. (2020). Hip and knee replacement in patients with ochronosis: Clinical experience and literature review. Orthopedic Reviews, 12(1s). https://doi.org/10.4081/or.2020.8687