Evaluation of the effectiveness of an aromatherapy treatment with lavender essential oil to reduce post-operative nausea and vomiting: study protocol of a randomised controlled trial


Submitted: 17 February 2023
Accepted: 1 March 2023
Published: 31 March 2023
Abstract Views: 679
PDF: 197
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

  • Tatiana Bolgeo SC Research Training Innovation Infrastructure, Integrated Activities, Research, Innovation Department (DAIRI), SS Antonio e Biagio e Cesare Arrigo National Hospital Alessandria, Italy. https://orcid.org/0000-0002-7322-7009
  • Laura Savi SC Hospital Pharmacy Device and Drug Management, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria, Italy.
  • Pietro Ricci SC Directorate of Health Professions, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria, Italy.
  • Elisabetta Zogno SC Neurosurgery, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria, Italy.
  • Giovanna Drago SC General Surgery, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria, Italy.
  • Sara Gallesi SC Vascular Surgery, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria, Italy.
  • Barbara Fadda SS Gynaecological Surgery, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria, Italy.
  • Denise Gatti SC Research Training Innovation Infrastructure, Integrated Activities, Research, Innovation Department (DAIRI), SS Antonio e Biagio e Cesare Arrigo National Hospital Alessandria, Italy. https://orcid.org/0000-0001-9806-5360
  • Menada Gardalini SC Research Training Innovation Infrastructure, Integrated Activities, Research, Innovation Department (DAIRI), SS Antonio e Biagio e Cesare Arrigo National Hospital Alessandria, Italy.
  • Roberta Di Matteo SC Research Training Innovation Infrastructure, Integrated Activities, Research, Innovation Department (DAIRI), SS Antonio e Biagio e Cesare Arrigo National Hospital Alessandria, Italy. https://orcid.org/0000-0001-8249-8284
  • Antonio Maconi SC Research Training Innovation Infrastructure, Integrated Activities, Research, Innovation Department (DAIRI), SS Antonio e Biagio e Cesare Arrigo National Hospital Alessandria, Italy.

Background: The most common post-operative symptoms are nausea and vomiting. Aromatherapy has been shown to reduce post-operative nausea and vomiting and thus could be used as a complementary therapy to antiemetic drugs; however, no studies have considered the exclusive use of Lavender in these patients. The study’s aim is to assess aromatherapy in reducing nausea and vomiting in post-operative patients. Materials and Methods: A 2-arm randomised controlled interventional study was carried out in the Neurosurgery, General Surgery, Vascular Surgery, and Gynaecology facilities of the SS Antonio e Biagio e Cesare Arrigo Hospital of Alessandria. Study inclusion criteria: patients over the age of 18, who sign an informed consent form, have had an anaesthesiologic examination, have had general anaesthesia, and are clinically stable with a nausea score of NRS>0. Multiple instruments will be used, including a numerical rating scale, a Likert rating scale, and a Likert rating scale to assess Vomiting and the degree of satisfaction. Conclusions: The use of complementary non-pharmacological methods such as aromatherapy may help patients feel more comfortable in the post-operative period.


Asay K, Olson C, Donnelly J, Perlman E. The Use of Aromatherapy in Postoperative Nausea and Vomiting: A Systematic Review. J Perianesthesia Nurs Off J Am Soc PeriAnesthesia Nurses. 2019;34:502–16. DOI: https://doi.org/10.1016/j.jopan.2018.08.006

Hodge NS, McCarthy MS, Pierce RM. A Prospective Randomized Study of the Effectiveness of Aromatherapy for Relief of Postoperative Nausea and Vomiting. J Perianesth Nurs. 2014;29:5–11. DOI: https://doi.org/10.1016/j.jopan.2012.12.004

Pierre S, Whelan R. Nausea and vomiting after surgery. Contin Educ Anaesth Crit Care Pain. 2013;13:28–32. DOI: https://doi.org/10.1093/bjaceaccp/mks046

Rajan N, Joshi GP. Management of postoperative nausea and vomiting in adults: current controversies. Curr Opin Anaesthesiol. 2021;34:695–702. DOI: https://doi.org/10.1097/ACO.0000000000001063

Ferruggiari L, Ragione B, Rich ER, Lock K. The Effect of Aromatherapy on Postoperative Nausea in Women Undergoing Surgical Procedures. J Perianesth Nurs. 2012;27:246–51. DOI: https://doi.org/10.1016/j.jopan.2012.01.013

Jin Z, Gan TJ, Bergese SD. Prevention and Treatment of Postoperative Nausea and Vomiting (PONV): A Review of Current Recommendations and Emerging Therapies. Ther Clin Risk Manag. 2020;16:1305–17. DOI: https://doi.org/10.2147/TCRM.S256234

Hudgens A, Hunt R, Dienemann J, et al. Postoperative Nausea and Vomiting Rescue Using Aromatherapy. J Perianesth Nurs. 2013;28:e46–7. DOI: https://doi.org/10.1016/j.jopan.2013.04.134

Bamgbade OA, Oluwole O, Khaw RR. Perioperative Antiemetic Therapy for Fast-Track Laparoscopic Bariatric Surgery. Obes Surg. 2018;28:1296–301. DOI: https://doi.org/10.1007/s11695-017-3009-7

Sites DS, Johnson NT, Miller JA, et al. Controlled Breathing With or Without Peppermint Aromatherapy for Postoperative Nausea and/or Vomiting Symptom Relief: A Randomized Controlled Trial. J Perianesth Nurs. 2014;29:12–9. DOI: https://doi.org/10.1016/j.jopan.2013.09.008

Hall PED, Card EB. Uses of Complementary and Alternative Medicine for Perioperative and Other Patients. Nurs Clin North Am. 2020;55:537–42. DOI: https://doi.org/10.1016/j.cnur.2020.06.020

Beyliklioğlu A, Arslan S. Effect of Lavender Oil on the Anxiety of Patients Before Breast Surgery. J Perianesth Nurs. 2019;34:587–93. DOI: https://doi.org/10.1016/j.jopan.2018.10.002

Yayla EM, Ozdemir L. Effect of Inhalation Aromatherapy on Procedural Pain and Anxiety After Needle Insertion Into an Implantable Central Venous Port Catheter: A Quasi-Randomized Controlled Pilot Study. Cancer Nurs. 2019;42:35–41. DOI: https://doi.org/10.1097/NCC.0000000000000551

Franco L, Blanck TJJ, Dugan K, et al. Both lavender fleur oil and unscented oil aromatherapy reduce preoperative anxiety in breast surgery patients: a randomized trial. J Clin Anesth. 2016;33:243–9. DOI: https://doi.org/10.1016/j.jclinane.2016.02.032

Karadag E, Samancioglu S, Ozden D, Bakir E. Effects of aromatherapy on sleep quality and anxiety of patients: Effects of aromatherapy on sleep quality and anxiety of patients. Nurs Crit Care. 2017;22:105–12. DOI: https://doi.org/10.1111/nicc.12198

Karaman S, Karaman T, Tapar H, et al. A randomized placebo-controlled study of aromatherapy for the treatment of postoperative nausea and vomiting. Complement Ther Med. 2019;42:417–21.

Hunt R, Dienemann J, Norton HJ, et al. Aromatherapy as Treatment for Postoperative Nausea: A Randomized Trial. Anesth Analg. 2013;117:597–604. DOI: https://doi.org/10.1213/ANE.0b013e31824a0b1c

Karaman S, Karaman T, Tapar H, et al. A randomized placebo-controlled study of aromatherapy for the treatment of postoperative nausea and vomiting. Complement Ther Med. 2019;42:417–21. DOI: https://doi.org/10.1016/j.ctim.2018.12.019

Wikström L, Nilsson M, Broström A, Eriksson K. Patients’ self-reported nausea: Validation of the Numerical Rating Scale and of a daily summary of repeated Numerical Rating Scale scores. J Clin Nurs. 2019;28:959–68. DOI: https://doi.org/10.1111/jocn.14705

Shaikh SI, Nagarekha D, Hegade G, Marutheesh M. Postoperative nausea and vomiting: A simple yet complex problem. Anesth Essays Res. 2016;10:388. DOI: https://doi.org/10.4103/0259-1162.179310

Karaman T, Karaman S, Dogru S, et al. Evaluating the efficacy of lavender aromatherapy on peripheral venous cannulation pain and anxiety: A prospective, randomized study. Complement Ther Clin Pract. 2016;23:64–8. DOI: https://doi.org/10.1016/j.ctcp.2016.03.008

Algieri F, Rodriguez-Nogales A, Vezza T, et al. Anti-inflammatory activity of hydroalcoholic extracts of Lavandula dentata L. and Lavandula stoechas L. J Ethnopharmacol. 2016;190:142–58. DOI: https://doi.org/10.1016/j.jep.2016.05.063

Cardia GFE, Silva-Filho SE, Silva EL, et al. Effect of Lavender (Lavandula angustifolia) Essential Oil on Acute Inflammatory Response. Evid Based Complement Alternat Med. 2018;2018:e1413940. DOI: https://doi.org/10.1155/2018/1413940

Raisi Dehkordi Z, Hosseini Baharanchi FS, Bekhradi R. Effect of lavender inhalation on the symptoms of primary dysmenorrhea and the amount of menstrual bleeding: A randomized clinical trial. Complement Ther Med. 2014;22:212–9. DOI: https://doi.org/10.1016/j.ctim.2013.12.011

Mellinger PIU, Lakdawala CIL. Aromatherapy to The Rescue for Postoperative Nausea and Vomiting. J Perianesth Nurs. 2021;36:e26–7. DOI: https://doi.org/10.1016/j.jopan.2021.06.078

Tatiana Bolgeo, SC Research Training Innovation Infrastructure, Integrated Activities, Research, Innovation Department (DAIRI), SS Antonio e Biagio e Cesare Arrigo National Hospital Alessandria

 

 

Laura Savi, SC Hospital Pharmacy Device and Drug Management, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria

 

 

 

Pietro Ricci, SC Directorate of Health Professions, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria

 

 

 

Elisabetta Zogno, SC Neurosurgery, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria

 

 

Giovanna Drago, SC General Surgery, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria

 

 

 

Sara Gallesi, SC Vascular Surgery, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria

 

 

 

Barbara Fadda, SS Gynaecological Surgery, SS Antonio e Biagio e Cesare Arrigo National Hospital, Alessandria

 

 

 

Menada Gardalini, SC Research Training Innovation Infrastructure, Integrated Activities, Research, Innovation Department (DAIRI), SS Antonio e Biagio e Cesare Arrigo National Hospital Alessandria

 

 

Roberta Di Matteo, SC Research Training Innovation Infrastructure, Integrated Activities, Research, Innovation Department (DAIRI), SS Antonio e Biagio e Cesare Arrigo National Hospital Alessandria

 

 

Antonio Maconi, SC Research Training Innovation Infrastructure, Integrated Activities, Research, Innovation Department (DAIRI), SS Antonio e Biagio e Cesare Arrigo National Hospital Alessandria

 

 

Bolgeo, T., Savi, L., Ricci, P., Zogno, E., Drago, G., Gallesi, S., Fadda, B., Gatti, D., Gardalini, M., Di Matteo, R., & Maconi, A. (2023). Evaluation of the effectiveness of an aromatherapy treatment with lavender essential oil to reduce post-operative nausea and vomiting: study protocol of a randomised controlled trial. Working Paper of Public Health, 11(1). https://doi.org/10.4081/wpph.2023.9690

Downloads

Download data is not yet available.

Citations