The great imitator, revisited
https://doi.org/10.4081/dr.2022.9363
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Our study shows an atypical presentation of primary syphilis inappropriately treated with surgery: a 36-year-old male visited our clinic for a consultation 2 weeks after surgery, since he had noticed a recurrent lesion on the glans head of the penis. Clinical data, histologic pictures and serological tests, confirmed the diagnosis of an atypical presentation of primary syphilis; in addition, Chlamydia trachomatis infection was found. The patient was started on a course of doxycycline 100 mg tablets, twice daily for 4 weeks. At follow up, there was complete remission.
World Health Organisation. WHO Guidelines for the Treatment of Treponema pallidum (Syphilis). WHO Press, World Health Organisation
Dai T, Qu R, Liu J, et al. Efficacy of Doxycycline in the Treatment of Syphilis. Antimicrob Agents Chemother 2017;61:e01092-16 DOI: https://doi.org/10.1128/AAC.01092-16
Klausner J. The Great Imitator Revealed: Syphilis. Top Antivir Med 2019;27:71-4.
Rockwood N, Nwokolo N. Syphilis the great pretender: when is cancer not cancer? BMJ: Sexual Transmit Infect 2018;94. DOI: https://doi.org/10.1136/sextrans-2017-053508
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