Maculopapular sarcoidosis: the importance of skin signs


Published: 16 September 2022
Abstract Views: 602
PDF: 207
HTML: 10
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Sarcoidosis is a multisystem disease that affects the skin in 20 to 30% of cases. Skin findings are often the initial presenting signs, and cutaneous sarcoidosis may appear with a wide variety of lesions; it is often considered an imitator of many other skin diseases. Clinical appearance and specific dermoscopic criteria, confirmed by a typical pathology, may guide to the correct diagnosis. We report the case of a man affected by maculo-papular sarcoidosis on the back, in which the detection of cutaneous lesions was the initial step to determine the systemic nature of the disease.


Soto-Gomez N, Peters JI, Nambiar AM. Diagnosis and management of sarcoidosis. Am Fam Physician 2016;93:840-8.

Hena KM. Sarcoidosis epidemiology: race matters. Front Immunol 2020;11:537382.

Statement on sarcoidosis. Joint statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS board of directors and by the ERS Executive Committee, February 1999. Am J Respir Crit Care Med 1999;160:736-55.

Hoffmann AL, Milman N, Byg KE. Childhood sarcoidosis in Denmark 1979-1994: incidence, clinical features and laboratory results at presentation in 48 children. Acta Paediatr 2004;93:30-6.

Müller-Quernheim J, Schürmann M, Hofmann S, et al. Genetics of sarcoidosis. Clin Chest Med 2008;29:391-414.

Rybicki BA, Walewski JL, Maliarik MJ, et al. The BTNL2 gene and sarcoidosis susceptibility in african americans and whites. Am J Hum Genet 2005;77:491–9.

Gray-McGuire C, Sinha R., Iyengar S, et al. Genetic characterization and fine mapping of susceptibility loci for sarcoidosis in African Americans on chromosome 5. Hum Genet 2006;120:420-30

Crouser ED, Maier LA, Wilson KC, et al. Diagnosis and detection of sarcoidosis. An official american thoracic society clinical practice guideline. Am J Respir Crit Care Med 2020; 201:e26–51.

Gerke AK. Treatment of sarcoidosis: a multidisciplinary approach. Front Immunol 2020;11:545413.

Belkhou A, Younsi R, El Bouchti I, et al. Rituximab as a treatment alternative in sarcoidosis. Joint Bone Spine 2008;75:511–2.

Baughman RP, Judson MA, Ingledue R, et al. Efficacy and safety of apremilast in chronic cutaneous sarcoidosis. Arch Dermatol 2012;148:262–4.

Judson MA, Baughman RP, Costabel U, et al. Safety and efficacy of ustekinumab or golimumab in patients with chronic sarcoidosis. Eur Respir J 2014;44:1296–307.

Tan JL, Fong HK, Birati EY, Han Y. Cardiac sarcoidosis. Am J Cardiol 2019;123:513-22 .

Wu JJ, Schiff KR. Sarcoidosis. Am Fam Physician 2004;70:312-22.

Caplan A, Rosenbach M, Imadojemu S. Cutaneous sarcoidosis. Semin Respir Crit Care Med 2020;41:689–99.

Haimovic A, Sanchez M, Judson MA, Prystowsky S. Sarcoidosis: a comprehensive review and update for the dermatologist. J Am Acad Dermatol 2012;66:719.e1–10.

Prasse A. The diagnosis, differential diagnosis, and treatment of sarcoidosis. Dtsch Arztebl Int 2016;113:565-74.

Galdo, G., Luongo, G., Capacchione, D., Abeni, D., Grimaldi, M., & Fania, L. (2022). Maculopapular sarcoidosis: the importance of skin signs. Dermatology Reports, 15(1). https://doi.org/10.4081/dr.2022.9561

Downloads

Download data is not yet available.

Citations

Similar Articles

You may also start an advanced similarity search for this article.