New cases of childhood leprosy in two male siblings in low endemic province: an iceberg phenomenon?


Published: 19 May 2023
Abstract Views: 699
PDF: 349
HTML: 1
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Children are the leprosy population most at risk; multibacillary infections are common. We reported pediatric cases with WHO-multibacillary lepromatous type morbus Hansen. We discovered several hypopigmented patches on the right upper arm, anesthesia-filled claw hands, and infiltrates in the ears in one 17- year-old child. In the other case (13-year-old), we discovered reduced sensory sensitivity in nearly every area of the body, infiltrates on the ear, and numerous irregular hypopigmented plaques on the belly, lumbar, and gluteus. Both patients had positive acidfast bacteria. After three months of treatment, multibacillary leprosy patients began to show improvement. Low socioeconomic and environmental conditions, as well as a history of intimate contact with leprosy patients, have been identified as risk factors.


Sangupta U. Recent Laboratory Advances in Diagnostics and Monitoring Response to Treatment in Leprosy. Indian Dermatol Online J, 2019;10:106–114. DOI: https://doi.org/10.4103/idoj.IDOJ_260_18

White C, Franco-Paredes C. Leprosy in the 21st century. Clin Microbiol Rev, 2015;28:80–94 DOI: https://doi.org/10.1128/CMR.00079-13

World Health Organizations. Leprosy, 2022. Available from: https://www.who.int/news-room/fact-sheets/detail/leprosy

Kementrian Kesehatan RI. Profil Kesehatan Indonesia Tahun 2021. Kementrian Kesehatan RI, 2022.

Ogunsumi, DO. et al. Measuring endemicity and burden of leprosy across countries and regions: A systematic review and Delphi survey. PloS Negl Trop Dis, 2021;15:1-19. DOI: https://doi.org/10.1371/journal.pntd.0009769

Dinas Kesehatan Provinsi NTB. Profil Kesehatan Provinsi NTB Tahun 2021. Kementrian Kesehatan RI, 2022.

Affarah WS, Primayanti I, Sari LS. Gambaran Epidemiologi Kusta Pada Anak Dan Pelaksanaan Kemoprofilaksis Kusta Di Kota Mataram. J Kedokt Unram, 2021;10:413–421. DOI: https://doi.org/10.29303/jku.v10i2.530

Ruiz-Fuentes JL, Rumbaut Castillo R, Hurtado Gascón LdlC, Pastrana F. Leprosy in children: a Cuban experience on leprosy control. BMJ Paediatrics Open, 2019;3:1–7. DOI: https://doi.org/10.1136/bmjpo-2019-000500

Sotiriou MC, Stryjewska BM, Hill C. Case Report : Two Cases of Leprosy in Siblings Caused by Mycobacterium lepromatosis and Review of the Literature. Am J Trop Med Hyg, 2016;95:522–527. DOI: https://doi.org/10.4269/ajtmh.16-0076

Gracino ME, Mendes B, Garbelin MV, Nishi V, Silva D, et al. Leprosy : A systematic review. International Journal of Dermatology Sciences, 2020;2:08-21. DOI: https://doi.org/10.33545/26649772.2020.v2.i1a.10

Mira MT, Alcais A, Nguyen VT, Moraes MO,et al. Susceptibility to leprosy is associated with PARK2 and PACRG. Nature, 2004;427:636-640. DOI: https://doi.org/10.1038/nature02326

Cendaki QA. The Findings of Mycobacterium Leprae DNA Existence in the Air as an Indication of Leprosy Transmission from Respiratory System. J Kesehat Lingkung. 2018;10:181-190. DOI: https://doi.org/10.20473/jkl.v10i2.2018.181-190

Kementrian Republik Indonesia. Peraturan Menteri Kesehatan Republik Indonesia Nomor 11 Tahun 2019 Tentang Penanggulangan Kusta. 2019.

Pratama N, Mas-Rusyati LM, Sudarsa PS, et al. Borderline Lepromatous Leprosy with Severe Erythema Nodusum Leprosum: A Case Report. Available from: https://e-journal.unair.ac.id/BIKK

Jariyakulwong N, Julanon N, Saengboonmee C. Lepromatous leprosy with a suspected 30-year incubation period: A case report of a practically eradicated area. J Taibah Univ Med Sc, 2022; 17: 602-605. DOI: https://doi.org/10.1016/j.jtumed.2021.12.005

Richardus JH, et al. Leprosy post-exposure prophylaxis with single-dose rifampicin (LPEP): an international feasibility programme. Lancet Glob Health, 2021;9:e81-e90. DOI: https://doi.org/10.1016/S2214-109X(20)30396-X

I Gusti Ayu Febi Risantari, Department of Dermatology and Venereology, West Nusa Tenggara General Hospital, Lombok

Apprentice

Hidajat, D., Risantari, I. G. A. F., & Affarah, W. S. (2023). New cases of childhood leprosy in two male siblings in low endemic province: an iceberg phenomenon?. Dermatology Reports, 15(4). https://doi.org/10.4081/dr.2023.9706

Downloads

Download data is not yet available.

Citations