Linear immunoglobulin A bullous dermatosis induced by atezolizumab
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Linear immunoglobulin A bullous dermatosis (LABD) is a rare immune-mediated vesiculobullous disease that is reported to be induced by infections or medications. Atezolizumab is a monoclonal antibody that targets programmed cell death ligand-1 and has been used to treat multiple cancers. Here, we report a case of drug induced LABD following the administration of atezolizumab.
Bernett CN, Fong M, Yadlapati S, Rosario-Collazo JA. Linear IgA dermatosis. Treasure Island (FL): StatPearls Publishing; 2022.
Lammer J, Hein R, Roenneberg S, et al. Drug-induced linear IgA bullous dermatosis: a case report and review of the literature. Acta Dermatol Venereol 2019;99:508-15.
Sibaud V, Meyer N, Lamant L, et al. Dermatologic complications of anti-PD-1/PD-L1 immune checkpoint antibodies. Curr Opin Oncol 2016;28:254-63.
Aguilar‐Duran S, Mee J, Popat S, Heelan K. Atezolizumab‐induced linear IgA bullous dermatosis. Br J Dermatol 2022;187:e193.
Yawalkar N, Reimers A, Hari Y, et al. Drug-induced linear IgA bullous dermatosis associated with ceftriaxone-and metronidazole-specific T cells. Dermatology 1999;199:25-30.
Herbst RS, Soria JC, Kowanetz M, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 2014;515:563-7.
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