Clinical picture, diagnosis and treatment of rosacea, complicated by Demodex mites

  • Alexey Kubanov Russian Medical Academy of Continuous Professional Education, Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation.
  • Yuliya Gallyamova | yulya.gallyamova.69@mail.ru Russian Medical Academy of Continuous Professional Education, Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation.
  • Anzhela Kravchenko Russian Medical Academy of Continuous Professional Education, Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation.

Abstract

The article analyzes the clinical picture and course of rosacea in patients with Demodex mites. It presents the advantages of using the method of confocal laser scanning microscopy over the method of light microscopy of facial skin scrapes. The aimes were to study the influence of Demodex mites on the clinical picture and course of rosacea; to compare laboratory and instrumental diagnostic methods for detecting Demodex mites; to evaluate the effectiveness of external therapy aimed at eliminating Demodex mites. 212 people were examined. The study included healthy patients, patients with a diagnosis of rosacea with the presence and absence of Demodex. The presence of Demodex mites was confirmed by two methods of study (light microscopy of skin scrapes and confocal laser scanning in vivo microscopy). Demodex mites promote the development of acute-inflammatory morphological elements, increase the duration of the condition (more than 5 years, P<0.01) and the probability of recurrence (from 1 to 3 relapses in 39.5% of patients, P<0.05), resulting in a decrease in the quality of life of patients (dermatology life quality index is 12.5±4.5, P<0.05). Antiparasitic drug ivermectin, in the form of an external form, at a concentration of 1% has a high therapeutic efficacy (in 93.3% of cases). Demodex folliculorum shows signs of parasitism, while Demodex folliculorum brevis is a saprophyte. The severity of the condition does not depend on the quantitative load of the mites in the scrape. As an antiparasitic drug, it is recommended to use 1% ivertmectin.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.
Published
2019-03-28
Info
Issue
Section
Articles
Keywords:
dermatology life quality index, Demodex mites, Demodex folliculorum, Demodex folliculorum brevis.
Statistics
  • Abstract views: 1148

  • PDF: 345
  • HTML: 47
How to Cite
Kubanov, A., Gallyamova, Y., & Kravchenko, A. (2019). Clinical picture, diagnosis and treatment of rosacea, complicated by Demodex mites. Dermatology Reports, 11(1). https://doi.org/10.4081/dr.2019.7675