Bullous mycosis fungoides associated with an extensive ulcer and a severe leukemoid reaction

  • Shuei Sato Department of Dematology, Faculty of medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu-shi, Oita, Japan.
  • Osamu Okamoto | ookamoto@oita-u.ac.jp Department of Dematology, Faculty of medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu-shi, Oita, Japan.
  • Michifumi Kawamoto Department of Dematology, Faculty of medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu-shi, Oita, Japan.
  • Masaki Oishi Department of Dematology, Faculty of medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu-shi, Oita, Japan.
  • Naomi Yada Department of Pathology, Faculty of medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu-shi, Oita, Japan.
  • Kazuhiro Kohno Hematological Unit of Internal Mrdicine, Faculty of medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu-shi, Oita, Japan.
  • Shigeo Yokoyama Department of Pathology, Faculty of medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu-shi, Oita, Japan.
  • Sakuhei Fujiwara Department of Dematology, Faculty of medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu-shi, Oita, Japan.

Abstract

This report presents a case of bullous mycosis fungoides associated with an extensive ulcer and a severe leukemoid reaction. The rash began as indurated erythema which was always followed by ulceration. The rashes initially responded to radiation therapy, but multiple recurrences appeared. Several bullae appeared on the trunk during the course of the illness, without any evidence of paraneoplastic pemphigus. Finally, the ulcer covered a large part of the trunk, and the patient died of sepsis with an extreme leukocyte count of 118,000/μL. A bone marrow analysis revealed a leukemoid reaction and an autopsy revealed pseudomembranous colitis.

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Published
2011-12-02
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Section
Brief Reports
Keywords:
bullous mycosis fungoides, leukemoid reaction, pseudomembranous colitis.
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How to Cite
Sato, S., Okamoto, O., Kawamoto, M., Oishi, M., Yada, N., Kohno, K., Yokoyama, S., & Fujiwara, S. (2011). Bullous mycosis fungoides associated with an extensive ulcer and a severe leukemoid reaction. Dermatology Reports, 3(3), e54. https://doi.org/10.4081/dr.2011.e54