Promising 3D in vitro models for studying tumour heterogeneity and testing novel therapeutic approaches in pancreatic cancer


Published: 29 September 2021
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Authors

  • Stefania Forciniti Institute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce; Department of Neurosciences, Biomedicine and Movement Sciences, Biochemistry Section, University of Verona, Italy.
  • Marta Cavo Institute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce, Italy.
  • Ilaria Dando Department of Neurosciences, Biomedicine and Movement Sciences, Biochemistry Section, University of Verona, Italy.
  • Elisa Dalla Pozza Department of Neurosciences, Biomedicine and Movement Sciences, Biochemistry Section, University of Verona, Italy.
  • Marta Palmieri Department of Neurosciences, Biomedicine and Movement Sciences, Biochemistry Section, University of Verona, Italy.
  • Loretta L. del Mercato Institute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce, Italy.

In this study we produced 3D organotypic cultures and spheroids to mimic the complex microenvironment of pancreatic cancer and to test alternative therapeutic strategies.


Forciniti, S., Cavo, M., Dando, I., Dalla Pozza, E. ., Palmieri, M., & del Mercato, L. L. . (2021). Promising 3D <em>in vitro</em> models for studying tumour heterogeneity and testing novel therapeutic approaches in pancreatic cancer. Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.169

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