Toward scalable in vitro models: a novel experimental and computational pipeline for the identification of cellular metabolic parameters
https://doi.org/10.4081/bse.179
Published: 29 September 2021
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Oxygen utilization by cells has a crucial role in the design of advanced in vitro models. The aim of this study is to develop an experimental and computational pipeline for identifying oxygen metabolism parameters. We applied the approach to HepG2 cell monolayer cultures, demonstrating that such parameters depend on cell density.
Mancini, P., Botte, E., Magliaro, C., & Ahluwalia, A. (2021). Toward scalable <em>in vitro</em> models: a novel experimental and computational pipeline for the identification of cellular metabolic parameters. Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.179
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